CHAPS(CAS: 75621-03-3)

CHAPS, or 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonic acid, is a zwitterionic surfactant commonly used in biochemical applications. It has the chemical formula C12H26N2O6S and is known for its ability to solubilize hydrophobic substances in aqueous solutions. CHAPS is non-ionic and has a neutral charge at physiological pH, making it suitable for preserving protein structures and facilitating purification processes.

CHAPS is widely used in pharmaceuticals, biotechnology, and research for its role as a detergent and solubilizing agent. It helps in the extraction and purification of membrane proteins, stabilizes proteins during storage, and is used in the formulation of liquid detergents. Additionally, CHAPS finds applications in the food industry as an emulsifier and in industrial processes for cleaning and dispersing applications.

CHAPS is generally considered safe when used under proper conditions, but it should be handled with care. It has low toxicity and is not classified as a hazardous substance under most safety standards. However, prolonged skin contact or inhalation may cause irritation, so protective gloves and masks are recommended. Always follow standard laboratory safety protocols when working with CHAPS.

CHAPS should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is typically kept in a sealed container at a temperature range of 15–25°C. Maintaining proper humidity levels is essential to prevent degradation, and it should be stored in a non-corrosive, airtight container to ensure stability and prolong shelf life.