2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione | CAS No. 75216-45-4

2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Basic Information

CAS Number

75216-45-4

Molecular Formula

C18H11NO3

Molecular Weight

289.29 g/mol

AD

Basic Physical Properties

c1ccc2c(c1)cc(c(n2)C3C(=O)c4ccccc4C3=O)O

InChI

InChI=1S/C18H11NO3/c20-14-9-10-5-1-4-8-13(10)19-16(14)15-17(21)11-6-2-3-7-12(11)18(15)22/h1-9,15,20H

InChIKey

FDTLQXNAPKJJAM-UHFFFAOYSA-N

LogP

3.1032000000000024

Topological Polar Surface Area

67.26 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

453

Synonyms & References

English

  • Solvent Yellow 114
  • Transparent Yellow G
  • C.I.Solvent Yellow 114
  • 1H-Indene-1,3(2H)-dione,2-(3-hydroxy-2-quinolinyl)-
  • C.I. 47020
  • Disperse Yellow 54
  • 2-(3-Hydroxy-2-quinolyl)-1,3-indandione
  • 1H-Indene-1,3(2H)-dione, 2-(3-hydroxy-2-quinolinyl)-
  • C.I. Solvent Yellow 114
  • Latyl Yellow 3G
  • C.I. DISPERSE YELLOW 54
  • 2-(3-hydroxyquinolin-2-yl)indene-1,3-dione
  • 3'-Hydroxyquinophthalone
  • 2-(3-hydroxyquinolin-2-yl)-1H-indene-1,3(2H)-dione
  • 3-Hydroxy-2-(1,3-indandione-2-yl)quinoline
  • 2-(3-Hydroxy-quinolin-2-yl)-indan-1,3-dione
  • 2-(3-Hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione
  • U69Y4Q67LZ
  • 2-(3-Hydroxy-2-quinolyl)-1,3-in

FAQ

What are the physical and chemical properties of 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4)?

2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4) is a solid with a crystalline form. Its molecular weight is approximately 334.34 g/mol. This compound has limited water solubility and is soluble in organic solvents like dichloromethane and ethanol. It is moderately reactive, particularly towards nucleophilic substitution reactions. It is stable under normal ambient conditions but should be stored in a dry environment to prevent hydrolysis.

How is 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4) typically synthesized?

2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4) is typically synthesized via a multistep process starting from 2-quinolinylindene. Key steps include the formation of the quinoline ring, followed by the introduction of the hydroxy group and the indene ring closure. Commonly used catalysts in the synthesis include palladium complexes. The overall yield is moderate, around 50-60%, and selectivity is high for the desired product.

What industries use 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4)?

2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4) is primarily used in the pharmaceutical industry for the development of novel drug candidates. It also finds applications in the polymer industry for the synthesis of advanced polymers and in the sensor industry for the fabrication of gas sensors. Additionally, it is used in semiconductor manufacturing for the production of organic semiconductors.

What precautions should be taken when handling 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4)?

When handling 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 75216-45-4), it is essential to wear appropriate personal protective equipment (PPE) including safety goggles, gloves, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling procedures and emergency response instructions.

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