6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid

Basic Information

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CAS Number

749849-14-7

Molecular Formula

C8H5BrN2O2

Molecular Weight

241.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.89

SMILES

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C1=CC2=NC(=CN2C=C1Br)C(=O)O

InChI

InChI=1S/C8H5BrN2O2/c9-5-1-2-7-10-6(8(12)13)4-11(7)3-5/h1-4H,(H,12,13)

InChIKey

FQBFPVLZLNEQOE-UHFFFAOYSA-N

LogP

1.795

Topological Polar Surface Area

54.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

224

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6-bromoimidazo[1,2-a]pyridine-2-carboxylic acid
MFCD04116918
Imidazo[1,2-a]pyridine-2-carboxylicacid,6-bromo-,hydrobromide(1:1)
6-Bromoimidazo[1 pound not2-a]pyridine-2-carboxylic acid
6-bromo-2-imidazo[1,2-a]pyridinecarboxylic acid
imidazo[1,2-a]pyridine-2-carboxylic acid, 6-bromo-
AKOS005143621
AMY28927
SS-4651
3-CHLORO-2,3,5,6-TETRAHYDRO-[1,2]BIPYRAZINYL-4-CARBOXYLICACIDTERT-BUTYLESTER
PB10307
EN300-92563
FT-0644868
FQBFPVLZLNEQOE-UHFFFAOYSA-N
A838292
J-518433
6-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
6-bromanylimidazo[1,2-a]pyridine-2-carboxylic acid
SY032086
SCHEMBL1500394
6-bromo-2-hydroxycarbonyl-imidazo[1,2-a]pyridine
DTXSID70373697
749849-14-7
CS-W022470
6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid
6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid hydrate
Imidazo[1,2-a]pyridine-2-carboxylicacid, 6-bromo-
6-bromo-4-hydroimidazo[1,2-a]pyridine-2-carboxylic acid
6-Bromo-imidazo[1,2-a]pyridine-2-carboxylic acid

MDL Number

MFCD04116918

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 749849-14-7)?

6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid is a solid at room temperature, with a molecular weight of approximately 262.04 g/mol. It has a low solubility in water but good solubility in organic solvents. The compound is moderately reactive, especially towards nucleophiles. It is stable in air but should be stored in a dry environment to avoid moisture absorption.

How is 6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 749849-14-7) typically synthesized?

6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid is typically synthesized via a multistep process involving the preparation of the imidazo[1,2-a]pyridine ring followed by bromination and carboxylation. Common catalysts include Lewis acids or Brønsted acids, and the reaction conditions should be carefully controlled to ensure high yield and selectivity.

What industries use 6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 749849-14-7)?

6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid is used in the pharmaceutical industry as a precursor for drug synthesis. It also finds applications in the development of sensors and as a building block in polymer chemistry. Additionally, it can be used in the synthesis of materials for semiconductors.

What precautions should be taken when handling 6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 749849-14-7)?

When handling 6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid, it is important to use personal protective equipment (PPE) such as gloves and goggles. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it is advisable to clean up with appropriate absorbent material and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed guidelines on handling and storage.