2-Chloro-5-methoxynicotinic acid

Basic Information

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CAS Number

74650-71-8

Molecular Formula

C7H6ClNO3

Molecular Weight

187.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC1=CC(=C(N=C1)Cl)C(=O)O

InChI

InChI=1S/C7H6ClNO3/c1-12-4-2-5(7(10)11)6(8)9-3-4/h2-3H,1H3,(H,10,11)

InChIKey

AJKXOHPNDQHYDM-UHFFFAOYSA-N

LogP

1.4418

Topological Polar Surface Area

59.42 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

176

Synonyms & References

English

SY097866
2-CHLORO-5-METHOXYPYRIDINE-3-CARBOXYLIC ACID
AMY33590
AKOS016008244
74650-71-8
2-Chloro-5-methoxynicotinic acid
FT-0764632
ZCA65071
AS-34753
2-chloro-5-Methoxy-3-pyridinecarboxylicacid
CS-0051945
2-Chloro-5-methoxynicotinicacid
A865841
AJKXOHPNDQHYDM-UHFFFAOYSA-N
2-CHLORO-5-METHOXY-3-PYRIDINECARBOXYLIC ACID
SCHEMBL10643500
DTXSID50511474
PB25567
MFCD16610607
2-Chloro-5-methoxy-3-pyridinecarboxylic acid
2-chloro-5-methoxypyridine-3-carboxylic acid
1598AC
FCH1178416
AK104612
AX8238820

MDL Number

MFCD16610607

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Chloro-5-methoxynicotinic acid (CAS: 74650-71-8)?

2-Chloro-5-methoxynicotinic acid is a crystalline solid with a molecular weight of approximately 192.59 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is known for its strong acidity and can undergo reactions such as esterification and nucleophilic substitution.

How is 2-Chloro-5-methoxynicotinic acid (CAS: 74650-71-8) typically synthesized?

2-Chloro-5-methoxynicotinic acid is commonly synthesized through the chlorination of 5-methoxynicotinic acid. This process typically involves the use of thionyl chloride as a chlorinating agent, followed by purification through recrystallization from a suitable solvent.

What industries use 2-Chloro-5-methoxynicotinic acid (CAS: 74650-71-8)?

2-Chloro-5-methoxynicotinic acid is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also used in the production of some agricultural chemicals and in the development of sensors.

What precautions should be taken when handling 2-Chloro-5-methoxynicotinic acid (CAS: 74650-71-8)?

When handling 2-Chloro-5-methoxynicotinic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a fume hood due to its potentially harmful vapors. Proper spill handling procedures should be followed, and the Safety Data Sheet (SDS) should be consulted for detailed safety information.