N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea | CAS No. 743458-79-9
N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea
Basic Information
CAS Number
743458-79-9
Molecular Formula
C24H20F12N4S2
Molecular Weight
656.56 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea
- N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea]
- N,N'-(1R,2R)-1,2-Cyclohexanediyl bis[N'-[3,5-bis(trifluoromethyl)phenyl)] -thiourea
MDL Number
MFCD31707558
FAQ
What are the physical and chemical properties of N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea] (CAS: 743458-79-9)?
The compound is a white crystalline solid with a high molecular weight. It has low solubility in water but good solubility in organic solvents. It is highly reactive due to the presence of thiourea and trifluoromethyl groups. Its melting point is around 260-262°C. This compound is not volatile and does not undergo hydrolysis under normal conditions. It is susceptible to thermal decomposition and reacts with strong acids and bases.
How is N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea] (CAS: 743458-79-9) typically synthesized?
This compound is synthesized via a multi-step process involving the coupling of thiourea derivatives with 1,2-cyclohexanediamine. The reaction is catalyzed by a palladium-based catalyst under mild conditions. The yield is typically around 70-80% and the selectivity is excellent. The synthesis requires careful control of reaction temperature and pressure to ensure product purity.
What industries use N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea] (CAS: 743458-79-9)?
This compound is primarily used in the pharmaceutical industry for its therapeutic properties and in the development of new drugs. It is also utilized in the sensor and semiconductor industries due to its unique chemical and physical properties, such as electronic conductivity. Additionally, it is used in polymer research for its potential to modify polymer properties.
What precautions should be taken when handling N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea] (CAS: 743458-79-9)?
When handling this compound, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It is advisable to work in a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Safe storage should be in a cool, dry place away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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