trans-1-Amino-1,3-cyclobutanedicarboxylic acid | CAS No. 73550-55-7

trans-1-Amino-1,3-cyclobutanedicarboxylic acid

Basic Information

CAS Number

73550-55-7

Molecular Formula

C6H9NO4

Molecular Weight

159.14 g/mol

AD

Basic Physical Properties

N[C@]1(C[C@H](C1)C(=O)O)C(=O)O

InChI

InChI=1S/C6H9NO4/c7-6(5(10)11)1-3(2-6)4(8)9/h3H,1-2,7H2,(H,8,9)(H,10,11)/t3-,6-

InChIKey

GGMYWPBNZXRMME-HSRNZHMGSA-N

LogP

-0.7368999999999997

Topological Polar Surface Area

100.62000000000002 Ų

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

196

Synonyms & References

English

  • 1,3-Cyclobutanedicarboxylicacid, 1-amino-, cis-
  • CIS-ACBD
  • cis-ACBD,cis-1-Aminocyclobutane-1,3-dicarboxylicacid
  • 1-amino-1,3-dicarboxycyclobutane
  • 1-AMINOCYCLOBUTANE-TRANS-1,3-DICARBOXYLIC ACID
  • 2-methanoglutamic acid
  • 5-Methylfurmethiodide
  • cis-1-amino-1,3-cyclobutanedicarboxylicacid
  • cis-1-Aminocyclobutan-1,3-dicarboxylic acid
  • CIS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
  • CIS-2,4-METHANOGLUTAMIC ACID
  • TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
  • trans-2,4-methanoglutamic acid
  • TRANS-ACBD
  • cis-1-aminocyclobutane-1,3-dicarboxylic acid

MDL Number

MFCD00153764

FAQ

What are the physical and chemical properties of trans-1-Amino-1,3-cyclobutanedicarboxylic acid (CAS: 73550-55-7)?

Trans-1-Amino-1,3-cyclobutanedicarboxylic acid is a solid with a crystalline form at room temperature. Its molecular weight is approximately 150.14 g/mol. This compound is slightly soluble in water but more soluble in organic solvents. It has moderate reactivity with carboxylic acid derivatives, and it can form esters and anhydrides under certain conditions. Additionally, it can react with amines to form amides.

How is trans-1-Amino-1,3-cyclobutanedicarboxylic acid (CAS: 73550-55-7) typically synthesized?

Trans-1-Amino-1,3-cyclobutanedicarboxylic acid can be synthesized through a multistep process involving the reaction of cyclobutanone with amines and carboxylation steps. Commonly, this involves reacting cyclobutanone with ammonia to form an intermediate, followed by the introduction of carboxylic acid groups. The process requires careful control of reaction conditions to achieve the desired isomer and yield.

What industries use trans-1-Amino-1,3-cyclobutanedicarboxylic acid (CAS: 73550-55-7)?

Trans-1-Amino-1,3-cyclobutanedicarboxylic acid is utilized in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the polymer industry to produce high-performance polymers with specific properties. Additionally, it finds applications in the production of sensors and semiconductors due to its unique chemical structure.

What precautions should be taken when handling trans-1-Amino-1,3-cyclobutanedicarboxylic acid (CAS: 73550-55-7)?

When handling trans-1-Amino-1,3-cyclobutanedicarboxylic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. Fume hoods should be used during operations involving the compound to minimize exposure. Spills should be cleaned up promptly using appropriate absorbent materials. It is advisable to refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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