4-Piperidinylacetic acid hydrochloride (1:1)

Basic Information

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CAS Number

73415-84-6

Molecular Formula

C7H14ClNO2

Molecular Weight

179.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

145-160°C

SMILES

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C1CNCCC1CC(=O)O.Cl

InChI

InChI=1S/C7H13NO2.ClH/c9-7(10)5-6-1-3-8-4-2-6;/h6,8H,1-5H2,(H,9,10);1H

InChIKey

IYDUFJOXYMLYNM-UHFFFAOYSA-N

LogP

0.8825000000000001

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

119

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SCHEMBL1967312
4-Piperidineacetic acid HCl
MFCD03414187
2I68Q70724
73415-84-6
PIPERIDIN-4-YL-ACETIC ACID HCL
4-Carboxymethylpiperidine hydrochloride
4-Piperidinylacetic acid hydrochloride, AldrichCPR
4-PIPERIDINEACETIC ACID, HCL
2-piperidin-4-ylacetic acid;hydrochloride
EN300-72832
UNII-2I68Q70724
PB18605
2-(piperidin-4-yl)acetic acid hydrochloride
2-(Piperidin-4yl)acetic acid hydrochloride
4-piperidineacetic acid hydrochloride, AldrichCPR
piperidin-4-ylacetic acid hydrochloride
4-Piperidineacetic acid, hydrochloride
CS-W001879
piperidin-4-yl acetic acid hydrochloride
SY006478
4-PIPERIDINEACETIC ACID HYDROCHLORIDE
PIPERIDINE-4-ACETIC ACID HYDROCHLORIDE
PIPERIDIN-4-YL-ACETIC ACID HYDROCHLORIDE
AKOS015847623
4-Piperidineacetic acid, hydrochloride (1:1)
AM20100706
IYDUFJOXYMLYNM-UHFFFAOYSA-N
4-Piperidine acetic acid Hydrochloride
2-(Piperidin-4-yl)acetic acid hydrochloride
4-piperidine acetic acid hydrochloride

MDL Number

MFCD03414187

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6)?

4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6) is a crystalline solid with a molecular weight of approximately 210.66 g/mol. It is sparingly soluble in water but soluble in organic solvents. Chemically, it is a weak acid with pKa values around 4.5-5.0. It is moderately reactive and can undergo basic hydrolysis under alkaline conditions.

How is 4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6) typically synthesized?

4-Piperidinylacetic acid hydrochloride is typically synthesized by reacting piperidine with acrylic acid in the presence of a suitable acid catalyst, such as sulfuric acid. The reaction is carried out under reflux conditions, and the product is isolated by recrystallization from water to form the hydrochloride salt. The yield is usually around 75-85%.

What industries use 4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6)?

4-Piperidinylacetic acid hydrochloride is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It also finds applications in the polymer industry as a stabilizer and in the production of biodegradable polymers. Additionally, it is used in the development of sensors for detecting metal ions and as a component in some organic semiconductor materials.

What precautions should be taken when handling 4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6)?

When handling 4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6), it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal procedures.