Compound Q&A

How is 4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6) typically synthesized?

Answer

4-Piperidinylacetic acid hydrochloride (1:1)
4-Piperidinylacetic acid hydrochloride is typically synthesized by reacting piperidine with acrylic acid in the presence of a suitable acid catalyst, such as sulfuric acid. The reaction is carried out under reflux conditions, and the product is isolated by recrystallization from water to form the hydrochloride salt. The yield is usually around 75-85%.

About

CAS No 73415-84-6
English Name 4-Piperidinylacetic acid hydrochloride (1:1)
Molecular Formula C7H14ClNO2
Molecular Weight 179.65 g/mol
SMILES C1CNCCC1CC(=O)O.Cl
InChIKey IYDUFJOXYMLYNM-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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