4-Piperidinylacetic acid hydrochloride (1:1)(CAS: 73415-84-6)

4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6) is a crystalline solid with a molecular weight of approximately 210.66 g/mol. It is sparingly soluble in water but soluble in organic solvents. Chemically, it is a weak acid with pKa values around 4.5-5.0. It is moderately reactive and can undergo basic hydrolysis under alkaline conditions.

4-Piperidinylacetic acid hydrochloride is typically synthesized by reacting piperidine with acrylic acid in the presence of a suitable acid catalyst, such as sulfuric acid. The reaction is carried out under reflux conditions, and the product is isolated by recrystallization from water to form the hydrochloride salt. The yield is usually around 75-85%.

4-Piperidinylacetic acid hydrochloride is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It also finds applications in the polymer industry as a stabilizer and in the production of biodegradable polymers. Additionally, it is used in the development of sensors for detecting metal ions and as a component in some organic semiconductor materials.

When handling 4-Piperidinylacetic acid hydrochloride (CAS: 73415-84-6), it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal procedures.