1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione

Basic Information

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CAS Number

7300-91-6

Molecular Formula

C10H7NO3

Molecular Weight

189.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

SMILES

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C1=CC(=CC=C1N2C(=O)C=CC2=O)O

InChI

InChI=1S/C10H7NO3/c12-8-3-1-7(2-4-8)11-9(13)5-6-10(11)14/h1-6,12H

InChIKey

BLLFPKZTBLMEFG-UHFFFAOYSA-N

LogP

0.8215999999999998

Topological Polar Surface Area

57.61 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

272

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

MFCD00129167
HMS2767A22
AMY619
7300-91-6
1H-pyrrole-2,5-dione, 1-(4-hydroxyphenyl)-
NCGC00245954-01
NSC39735
EINECS 230-750-6
CS-0157451
1-(4-Hydroxyphenyl)-2,5-dioxo-pyrrole
25989-83-7
NSC 39735
N-(p-hydroxyphenyl)maleimide
MLS000689806
GEO-04177
BDBM50300323
DTXSID90223286
AS-31855
AKOS002314125
1-(4-Hydroxy-phenyl)-pyrrole-2,5-dione
EU-0050807
cid_81734
GX66DA3FXR
NSC-39735
NSC148152
1-(4-Hydroxyphenyl)maleimide
NSC-148152
Z600448602
InChI=1/C10H7NO3/c12-8-3-1-7(2-4-8)11-9(13)5-6-10(11)14/h1-6,12
1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione
FT-0656066

MDL Number

MFCD00129167

Customs Code

2925190090

FAQ

What are the physical and chemical properties of 1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione (CAS: 7300-91-6)?

1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione is a crystalline solid with a molecular weight of approximately 208.15 g/mol. It has a solubility of about 1.4 g/L in water, and its melting point is around 168-169°C. The compound is known for its acidic nature due to the presence of the hydroxy group, which can participate in hydrogen bonding. Chemically, it is relatively stable but can undergo ring-opening reactions under basic conditions.

How is 1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione (CAS: 7300-91-6) typically synthesized?

1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione can be synthesized by the condensation reaction of 4-hydroxybenzaldehyde with 2,5-dione, typically using a catalyst such as p-toluenesulfonic acid (p-TSA). The reaction is carried out in a suitable solvent like toluene or acetic acid, providing a yield of around 90%. The process involves the formation of an intermediate, which is then converted to the final product.

What industries use 1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione (CAS: 7300-91-6)?

1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione finds applications in various industries. It is used in the pharmaceutical sector for the synthesis of certain drugs, in the polymer industry as a photoinitiator, and in the semiconductor industry for the production of photoresists. Additionally, it is utilized in the development of sensors for detecting specific chemical compounds.

What precautions should be taken when handling 1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione (CAS: 7300-91-6)?

When handling 1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dione, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or under a fume hood due to its potential for off-gassing. In case of a spill, it should be cleaned up using absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.