Diethyl (4-formylphenyl)phosphonate

Basic Information

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CAS Number

72436-45-4

Molecular Formula

C11H15O4P

Molecular Weight

242.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

SMILES

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CCOP(=O)(C1=CC=C(C=C1)C=O)OCC

InChI

InChI=1S/C11H15O4P/c1-3-14-16(13,15-4-2)11-7-5-10(9-12)6-8-11/h5-9H,3-4H2,1-2H3

InChIKey

KQJAWWYLJCTQNG-UHFFFAOYSA-N

LogP

2.3905000000000003

Topological Polar Surface Area

52.6 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

249

Safety Information

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Hazard Statement

Synonyms & References

English

DIETHYL(4-FORMYLPHENYL)PHOSPHONATE
72436-45-4
Diethyl (4-formylphenyl)phosphonate
Phosphonic acid, (4-formylphenyl)-, diethyl ester
DTXSID70378662
4-diethoxyphosphorylbenzaldehyde
GS-5491
Diethyl 4-formyl-benzenephosphonate
Diethyl 4-formyl-2-methoxyphenylphosphonate
H10269
diethyl 4-formylphenylphosphonate
CS-0212441
KQJAWWYLJCTQNG-UHFFFAOYSA-N
J-520298
SCHEMBL10168109
MFCD00272196
AKOS017343424
Phosphonic acid,P-(4-formylphenyl)-, diethyl ester
(4-formylphenyl)phosphonic acid diethyl ester
4-(diethoxyphosphoryl)benzaldehyde
4-(Diethyoxyphosphoryl)benzaldehyde
4-(phosphonate diethyl ester)benzaldehyde
diethyl 4-formylbenzphosphonate

MDL Number

MFCD00272196

FAQ

What are the physical and chemical properties of Diethyl (4-formylphenyl)phosphonate (CAS: 72436-45-4)?

Diethyl (4-formylphenyl)phosphonate is a colorless or pale yellow liquid with a molecular weight of approximately 241.24 g/mol. It is slightly soluble in water but highly soluble in organic solvents. The compound is known for its reactivity, particularly towards nucleophiles and bases, making it useful in various chemical reactions. It crystallizes in the orthorhombic system at room temperature.

How is Diethyl (4-formylphenyl)phosphonate (CAS: 72436-45-4) typically synthesized?

Diethyl (4-formylphenyl)phosphonate is typically synthesized by the reaction of diethyl phosphite with 4-formylphenol in the presence of a base such as sodium hydroxide. The reaction yields the target compound with high selectivity and good yield. Catalysts like pyridine are sometimes used to enhance selectivity and reaction rate.

What industries use Diethyl (4-formylphenyl)phosphonate (CAS: 72436-45-4)?

Diethyl (4-formylphenyl)phosphonate is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer chemistry for modifying properties of organic materials, in sensor technology for detection applications, and in semiconductor manufacturing for etching processes. Its versatility in organic synthesis makes it valuable across multiple sectors.

What precautions should be taken when handling Diethyl (4-formylphenyl)phosphonate (CAS: 72436-45-4)?

When handling Diethyl (4-formylphenyl)phosphonate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be carefully managed using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.