N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine | CAS No. 72324-18-6
N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine
Basic Information
CAS Number
72324-18-6
Molecular Formula
C10H11NO4S2
Molecular Weight
273.34 g/mol
AD
Basic Physical Properties
Melting Point
168-170°C
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Toxicity
LD50 in mice (mg/kg): >2500 orally, >1250 i.v.; in rats (mg/kg): >2500 orally, 1801 i.m. (Bolasco)
Synonyms & References
English
- AKOS015900589
- Tiofacic
- BDBM50248155
- Steproninum [INN-Latin]
- D07381
- N-(2-(2-Thienylcarbonylthio)propionyl)glycin
- (2-((thiophene-2-carbonyl)thio)propanoyl)glycine
- 2-(a-thenoylthio)propionylglycine
- Stepronine
- MLS006010031
- Stepronin [INN]
- 2-(2-(thiophene-2-carbonylthio)propanamido)acetic acid
- 0NOY894QRB
- STEPRONIN [WHO-DD]
- Tiase
- Stepronino [INN-Spanish]
- HY-A0234
- CHEBI:135129
- DB01423
- BCP13544
- Prostenoglycine
- Bronco-plus
- AS-13356
- Glycine, N-[1-oxo-2-[(2-thienylcarbonyl)thio]propyl]-
- CHEMBL2107531
- SCHEMBL19338
- AC-15511
- 2-(2-(thiophene-2-carbonylsulfanyl)propanoylamino)acetic acid
- W-104492
- FT-0630808
- Stepronine [INN-French]
MDL Number
MFCD00867405
FAQ
What are the physical and chemical properties of N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine (CAS: 72324-18-6)?
N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine is a crystalline compound with a molecular weight of approximately 331.32 g/mol. It has a solubility of about 0.1 g/L in water and exhibits moderate reactivity in acidic and basic conditions. This compound is typically stable under normal storage conditions but should be protected from moisture and heat.
How is N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine (CAS: 72324-18-6) typically synthesized?
N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine can be synthesized through a multi-step process involving thioether formation and esterification. Commonly, thiophene-2-carbonyl chloride reacts with propanoyl chloride to form the thioether, which is then coupled with glycine. The overall yield is around 75%, with good selectivity towards the desired product.
What industries use N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine (CAS: 72324-18-6)?
N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine finds applications in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also used in the polymer industry for the development of advanced materials and in the sensor industry for the fabrication of chemical sensors due to its unique functional groups.
What precautions should be taken when handling N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine (CAS: 72324-18-6)?
When handling N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. This compound should be stored in a cool, dry place, away from heat and moisture. In case of a spill, handle it using appropriate absorbents and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}
![N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}