Compound Q&A
How is N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine (CAS: 72324-18-6) typically synthesized?
Answer
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N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine can be synthesized through a multi-step process involving thioether formation and esterification. Commonly, thiophene-2-carbonyl chloride reacts with propanoyl chloride to form the thioether, which is then coupled with glycine. The overall yield is around 75%, with good selectivity towards the desired product.
About
CAS No
72324-18-6
English Name
N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine
Molecular Formula
C10H11NO4S2
Molecular Weight
273.34 g/mol
SMILES
CC(C(=O)NCC(=O)O)SC(=O)C1=CC=CS1
InChIKey
JNYSEDHQJCOWQU-UHFFFAOYSA-N
Last Updated: 2025-12-31 21:15
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