N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine(CAS: 72324-18-6)

N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine is a crystalline compound with a molecular weight of approximately 331.32 g/mol. It has a solubility of about 0.1 g/L in water and exhibits moderate reactivity in acidic and basic conditions. This compound is typically stable under normal storage conditions but should be protected from moisture and heat.

N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine can be synthesized through a multi-step process involving thioether formation and esterification. Commonly, thiophene-2-carbonyl chloride reacts with propanoyl chloride to form the thioether, which is then coupled with glycine. The overall yield is around 75%, with good selectivity towards the desired product.

N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine finds applications in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also used in the polymer industry for the development of advanced materials and in the sensor industry for the fabrication of chemical sensors due to its unique functional groups.

When handling N-{2-[(2-Thienylcarbonyl)sulfanyl]propanoyl}glycine, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. This compound should be stored in a cool, dry place, away from heat and moisture. In case of a spill, handle it using appropriate absorbents and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.