(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid | CAS No. 72217-12-0

(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid

Basic Information

CAS Number

72217-12-0

Molecular Formula

C5H6N4O3S

Molecular Weight

202.2 g/mol

AD

Basic Physical Properties

Melting Point

179-183°C

Density

1.83

CON=C(C1=NSC(=N1)N)C(=O)O

InChI

InChI=1S/C5H6N4O3S/c1-12-8-2(4(10)11)3-7-5(6)13-9-3/h1H3,(H,10,11)(H2,6,7,9)/b8-2-

InChIKey

OSIJZKVBQPTIMT-WAPJZHGLSA-N

LogP

-0.4445999999999999

Topological Polar Surface Area

110.69 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

234

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-[(Z)-methoxyimino]acetic acid
  • 72217-12-0
  • (2Z)-(MethoxyiMino)-2-(5-aMino-1,2,4-thiadiazol-3-yl)-acetic acid
  • AKOS025310149
  • (alphaZ)-5-Amino-alpha-(methoxyimino)-1,2,4-thiadiazole-3-acetic acid
  • AKOS015854880
  • BCP22885
  • 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)aceticacid
  • DTXSID601180764
  • LS-13040
  • 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid
  • (E)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid
  • 1,2,4-Thiadiazole-3-acetic acid, 5-amino-a-(methoxyimino)-, (aZ)-
  • 2-(5-Amino-1 pound not2 pound not4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid
  • 102297-34-7
  • (2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetic acid
  • SCHEMBL2454341
  • SCHEMBL2454344
  • 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid
  • 139183-37-2
  • ( Z ) -2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid
  • ATDA
  • ( Z )-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO ACETIC ACID (ATDA)
  • 2-(5-Amino-1,2,4-Thiadiazol-3-Yl)-2-(Methoxyimino)Acetic Acid
  • ( Z )-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid

MDL Number

MFCD08444061

Customs Code

2934999090

FAQ

What are the physical and chemical properties of (2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0)?

(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0) is a crystalline solid with a molecular weight of approximately 226.27 g/mol. It is slightly soluble in water and less soluble in common organic solvents. Chemically, the compound is known for its reactivity with metal ions and its ability to form stable complexes. It also shows good thermal stability, with a melting point around 200°C.

How is (2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0) typically synthesized?

(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0) is synthesized through multi-step organic reactions involving the condensation of 5-amino-1,2,4-thiadiazole with methoxyiminodiacetic acid. The synthesis typically involves the use of standard organic solvents and mild to moderate temperatures. The yield is usually around 70-80%, with good selectivity towards the desired product.

What industries use (2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0)?

(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0) is primarily used in pharmaceuticals and agricultural industries. It serves as a key intermediate in the production of drugs and as a fungicide. Its applications also extend to the development of sensors and other chemical reagents due to its unique chemical properties.

What precautions should be taken when handling (2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0)?

Precautions when handling (2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetic acid (CAS: 72217-12-0) include the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and away from heat sources. Spills should be cleaned up using absorbent materials and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.

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