2-Methoxy-1,3-thiazole-5-carboxylic acid | CAS No. 716362-09-3
2-Methoxy-1,3-thiazole-5-carboxylic acid
Basic Information
CAS Number
716362-09-3
Molecular Formula
C5H5NO3S
Molecular Weight
159.17 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- AKOS000320805
- AB50992
- MFCD09693857
- SCHEMBL1912573
- CS-0225143
- 2-METHOXY-5-THIAZOLECARBOXYLIC ACID
- EN300-1228851
- 2-methoxythiazole-5-carboxylic acid
- DTXSID90586181
- 2-METHOXY-THIAZOLE-5-CARBOXYLIC ACID
- 2-methoxythiazole-5-carboxylicacid
- F83109
- 5-Thiazolecarboxylicacid, 2-methoxy-
- GXPOIOYVYNLHLX-UHFFFAOYSA-N
- 716362-09-3
- 2-METHOXY-1,3-THIAZOLE-5-CARBOXYLIC ACID
- 5-Thiazolecarboxylicacid,2-methoxy-(9CI)
- 2-methoxy-1,3-thiazole-5-carboxylic acid
MDL Number
MFCD09693857
FAQ
What are the physical and chemical properties of 2-Methoxy-1,3-thiazole-5-carboxylic acid (CAS: 716362-09-3)?
2-Methoxy-1,3-thiazole-5-carboxylic acid is a white crystalline solid with a molecular weight of approximately 194.24 g/mol. It has a pKa of around 4.8 and is moderately soluble in water. This compound exhibits good reactivity with nucleophiles and can form amides, esters, and other derivatives. It is also known for its ability to act as a ligand in coordination chemistry.
How is 2-Methoxy-1,3-thiazole-5-carboxylic acid (CAS: 716362-09-3) typically synthesized?
2-Methoxy-1,3-thiazole-5-carboxylic acid can be synthesized via the reaction of 2-methoxythiazole with phthalimide under basic conditions in the presence of acetic anhydride. The synthesis typically involves careful control of pH and temperature to ensure high yield and selectivity. Alternative methods include the condensation of 2-methoxythiazole with aromatic amines followed by acidification.
What industries use 2-Methoxy-1,3-thiazole-5-carboxylic acid (CAS: 716362-09-3)?
2-Methoxy-1,3-thiazole-5-carboxylic acid is primarily used in the pharmaceutical industry as a precursor for organic synthesis, particularly in the development of anti-inflammatory and antimicrobial drugs. It also finds applications in the polymer industry for the synthesis of specialized polymers. Additionally, it is used in the production of sensors for detecting various chemicals and in semiconductor applications for doping processes.
What precautions should be taken when handling 2-Methoxy-1,3-thiazole-5-carboxylic acid (CAS: 716362-09-3)?
When handling 2-Methoxy-1,3-thiazole-5-carboxylic acid, it is essential to wear proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to prevent inhalation of vapor. Spills should be cleaned up according to the safety data sheet (SDS) guidelines. Disposal should be done according to local regulations, and the material should be stored in a cool, dry place away from direct sunlight and heat sources.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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