Compound Q&A

How is 2-Methoxy-1,3-thiazole-5-carboxylic acid (CAS: 716362-09-3) typically synthesized?

Answer

2-Methoxy-1,3-thiazole-5-carboxylic acid
2-Methoxy-1,3-thiazole-5-carboxylic acid can be synthesized via the reaction of 2-methoxythiazole with phthalimide under basic conditions in the presence of acetic anhydride. The synthesis typically involves careful control of pH and temperature to ensure high yield and selectivity. Alternative methods include the condensation of 2-methoxythiazole with aromatic amines followed by acidification.

About

English Name 2-Methoxy-1,3-thiazole-5-carboxylic acid
Molecular Formula C5H5NO3S
Molecular Weight 159.17 g/mol
SMILES COC1=NC=C(S1)C(=O)O
InChIKey GXPOIOYVYNLHLX-UHFFFAOYSA-N
Last Updated: 2026-03-04 16:30

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