2-Methyl-2-propanyl (4-aminophenyl)carbamate

Basic Information

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CAS Number

71026-66-9

Molecular Formula

C11H16N2O2

Molecular Weight

208.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Yellow to Brown Solid

Melting Point

114.0 to 118.0 deg-C

SMILES

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CC(C)(C)OC(=O)NC1=CC=C(C=C1)N

InChI

InChI=1S/C11H16N2O2/c1-11(2,3)15-10(14)13-9-6-4-8(12)5-7-9/h4-7H,12H2,1-3H3,(H,13,14)

InChIKey

WIVYTYZCVWHWSH-UHFFFAOYSA-N

LogP

2.6158

Topological Polar Surface Area

64.35 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

215

Safety Information

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GHS Hazard Pictograms

H302

H317

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

4-(t-butoxycarbonylamino)-aniline
tertbutyl 4-aminophenylcarbamate
CX1208
4-tert.butoxycarbonylamino-aniline
NS00060364
n-(tert-butoxycarbonyl)-1,4-phenylenediamine
4-(tert-Butoxycarbonylamino)aniline
CARBAMIC ACID, (4-AMINOPHENYL)-, 1,1-DIMETHYLETHYL ESTER
N-Boc-p-phenylenediamine, >=97.0% (NT)
4-tert-butoxycarbonylaminoaniline
4-amino-phenyl-carbamic acid tert-butyl ester
tert-butyl 4-aminophenylcarbamate
J-524839
N-Boc-benzene-1,4-diamine
N-BOC-1,4-PHENYLENE DIAMINE
tert-Butyl-4-aminophenylcarbamate
(4-aminophenyl)-carbamic acid tert butyl ester
A9331
AMY32316
N-(tert-Butoxycarbonyl)-p-phenylenediamine
DTXSID90991332
tert-Butyl (4-aminophenyl)carbamate
t-butyl (4-aminophenyl)carbamate
N-Boc-p-phenylenediamine
N-(t-butoxycarbonyl) 4-aminoaniline
N-tert-butoxycarbonyl-para-phenylenediamine
tert-butyl(4-aminophenyl)carbamate
4-(Boc-amino)aniline
B4081
mono-n-(t-butoxycarbonyl)-1,4-phenylenediamine
SCHEMBL78108

MDL Number

MFCD00043022

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (4-aminophenyl)carbamate (CAS: 71026-66-9)?

2-Methyl-2-propanyl (4-aminophenyl)carbamate is a solid compound with a crystalline form. Its molecular weight is approximately 231.28 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards acids and bases. It is stable under normal conditions but should be stored in a closed container away from strong acids and bases.

How is 2-Methyl-2-propanyl (4-aminophenyl)carbamate (CAS: 71026-66-9) typically synthesized?

2-Methyl-2-propanyl (4-aminophenyl)carbamate is synthesized through an amide coupling reaction. Typically, 2-propanol is reacted with 4-aminophenyl isocyanate in the presence of a coupling agent like 4-dimethylaminopyridine (DMAP) and a base such as triethylamine. The reaction is carried out at room temperature and provides a good yield with high selectivity.

What industries use 2-Methyl-2-propanyl (4-aminophenyl)carbamate (CAS: 71026-66-9)?

2-Methyl-2-propanyl (4-aminophenyl)carbamate is used in the pharmaceutical industry for the synthesis of certain drugs. It is also applicable in the polymer industry for the modification of polymer properties. Additionally, it can be used in the development of sensors and as a precursor in semiconductor manufacturing processes.

What precautions should be taken when handling 2-Methyl-2-propanyl (4-aminophenyl)carbamate (CAS: 71026-66-9)?

When handling 2-Methyl-2-propanyl (4-aminophenyl)carbamate, it is recommended to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled under a fume hood to avoid inhalation. Spills should be cleaned up using a suitable absorbent material and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage guidelines.