1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide

Basic Information

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CAS Number

701-44-0

Molecular Formula

C7H8N2O2

Molecular Weight

152.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

202-207°C (dec.)

SMILES

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CN1C=C(C=CC1=O)C(=O)N

InChI

InChI=1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)

InChIKey

JLQSXXWTCJPCBC-UHFFFAOYSA-N

LogP

-0.5158

Topological Polar Surface Area

65.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

266

Synonyms & References

English

N1-METHYL-2-PYRIDONE-5-CARBOXYAMIDE
3-Carbamoyl-1-methyl-6-pyridone
C76234
N'-Methyl-2-pyridone-5-carboxamide
1-Methyl-5-carboxylamide-2-pyridone
N1-Methyl-2-pyridone-5-carboxamide
1,6-Dihydro-1-methyl-6 -oxonicotinamide
BDBM50455093
1-Methyl-6-oxo-1 pound not6-dihydropyridine-3-carboxamide
NS00077092
AKOS003297743
N-Methyl-2-pyridoxone-5-carboxamide
2PY
SB76509
N(1)-methyl-2-pyridone-5-carboxamide
1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
JLQSXXWTCJPCBC-UHFFFAOYSA-N
Nudifloramide; LC-tDDA; CE10
CS-0059507
FT-0673170
CHEBI:27410
UNII-68139USC7W
1,6-Dihydro-1-methyl-6-oxonicotinamide
C05842
701-44-0
1-METHYL-6-PYRIDONE-3-CARBOXYLAMIDE
1-methyl-6-oxopyridine-3-carboxamide
FT-0673169
MFCD00457283
Nicotinamide, 1,6-dihydro-1-methyl-6-oxo-
1-Methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamide #

MDL Number

MFCD00457283

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS: 701-44-0)?

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide, also known as 6-oxo-1,6-dihydropyrido[3,2-b]pyridine-3-carboxamide, is a white crystalline solid (CAS: 701-44-0). Its molecular weight is approximately 229.24 g/mol. It is soluble in organic solvents such as methanol and dimethylformamide. This compound is relatively stable but can react with strong bases to form the corresponding amine. It is also known for its amphoteric nature.

How is 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS: 701-44-0) typically synthesized?

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide can be synthesized through a multi-step process involving the condensation of methyl acrylate and 2-pyridone, followed by oxidation. The reaction typically requires a catalyst such as concentrated sulfuric acid. The overall yield is moderate, and the product can be purified by crystallization from an appropriate solvent. This method allows for good selectivity and yields.

What industries use 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS: 701-44-0)?

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS: 701-44-0) finds applications in pharmaceuticals, where it serves as a precursor for drug development. It is also utilized in the production of polymers and as a component in sensors and semiconductors. Its structural properties make it suitable for various industrial applications.

What precautions should be taken when handling 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS: 701-44-0)?

When handling 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS: 701-44-0), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using an appropriate neutralizing agent and disposed of according to local regulations. It is recommended to consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.