Compound Q&A

How is 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS: 701-44-0) typically synthesized?

Answer

1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide can be synthesized through a multi-step process involving the condensation of methyl acrylate and 2-pyridone, followed by oxidation. The reaction typically requires a catalyst such as concentrated sulfuric acid. The overall yield is moderate, and the product can be purified by crystallization from an appropriate solvent. This method allows for good selectivity and yields.

About

CAS No 701-44-0
English Name 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
Molecular Formula C7H8N2O2
Molecular Weight 152.15 g/mol
SMILES CN1C=C(C=CC1=O)C(=O)N
InChIKey JLQSXXWTCJPCBC-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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