4-Chloro-2-fluoro-1-nitrobenzene

Basic Information

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CAS Number

700-37-8

Molecular Formula

C6H3ClFNO2

Molecular Weight

175.54 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

47.0 to 50.0 deg-C

Boiling Point

241.8℃ at 760 mmHg

Density

1.494

Flash Point

＞110℃

Refractive Index

1.531

SMILES

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C1=CC(=C(C=C1Cl)F)[N+](=O)[O-]

InChI

InChI=1S/C6H3ClFNO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H

InChIKey

PTCPUGKKWNMITF-UHFFFAOYSA-N

LogP

2.91050

Complexity

161

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-fluoro-4-chloro-nitrobenzene
4-chloro-2-fluoro-nitrobenzene
Benzene, 4-chloro-2-fluoro-1-nitro-
EINECS 211-842-5
DTXSID40220260
FT-0601438
1-chloro-3-fluoro-4-nitrobenzene
5-chloro-2-nitrofluorobenzene
MFCD00042211
4-chloro-2-fluoro-1-nitro benzene
AC-9689
A15951
SCHEMBL29348
4-Chloro-2-fluoro-1-nitrobenzene
W-202320
CS-W002202
AKOS005256685
EN300-152826
J-514942
PTCPUGKKWNMITF-UHFFFAOYSA-
4-Chloro-2-fluoro-1-nitrobenzene #
InChI=1/C6H3ClFNO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H
AS-14572
4-Chloro-2-fluoronitrobenzene
NS00042412
4-chloro-2-fluoro-1-nitro-benzene
AM20060201
2-FLUORO-4-CHLORONITROBENZENE
700-37-8
SY013131
2-fluoro-4-chloro-1-nitro-benzene

MDL Number

MFCD00042211

Customs Code

2904909090

FAQ

What are the physical and chemical properties of 4-Chloro-2-fluoro-1-nitrobenzene (CAS: 700-37-8)?

4-Chloro-2-fluoro-1-nitrobenzene is a solid with a melting point of 65-67°C. Its molecular weight is 194.01 g/mol. It is slightly soluble in water and readily soluble in organic solvents such as ethanol and acetone. It reacts readily with reducing agents and can undergo substitution reactions. This compound is used in the synthesis of other organic compounds.

How is 4-Chloro-2-fluoro-1-nitrobenzene (CAS: 700-37-8) typically synthesized?

4-Chloro-2-fluoro-1-nitrobenzene is synthesized by the nitration of 4-chloro-2-fluorobenzene. This is typically achieved using a mixture of nitric acid and sulfuric acid as the nitrating agent. The process is conducted at low temperatures to control the formation of undesired by-products. The yield is around 75-80%.

What industries use 4-Chloro-2-fluoro-1-nitrobenzene (CAS: 700-37-8)?

4-Chloro-2-fluoro-1-nitrobenzene is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of dyes, sensors, and as a precursor in the synthesis of other organic compounds.

What precautions should be taken when handling 4-Chloro-2-fluoro-1-nitrobenzene (CAS: 700-37-8)?

4-Chloro-2-fluoro-1-nitrobenzene should be handled in a well-ventilated area, preferably in a fume hood. It should be stored in a tightly closed container away from heat, sparks, and sources of ignition. In case of a spill, it is recommended to use appropriate PPE such as gloves, goggles, and a lab coat. Refer to the Safety Data Sheet (SDS) for more detailed handling and disposal information.