4-Chloro-2-fluoro-1-nitrobenzene(CAS: 700-37-8)

4-Chloro-2-fluoro-1-nitrobenzene is a solid with a melting point of 65-67°C. Its molecular weight is 194.01 g/mol. It is slightly soluble in water and readily soluble in organic solvents such as ethanol and acetone. It reacts readily with reducing agents and can undergo substitution reactions. This compound is used in the synthesis of other organic compounds.

4-Chloro-2-fluoro-1-nitrobenzene is synthesized by the nitration of 4-chloro-2-fluorobenzene. This is typically achieved using a mixture of nitric acid and sulfuric acid as the nitrating agent. The process is conducted at low temperatures to control the formation of undesired by-products. The yield is around 75-80%.

4-Chloro-2-fluoro-1-nitrobenzene is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of dyes, sensors, and as a precursor in the synthesis of other organic compounds.

4-Chloro-2-fluoro-1-nitrobenzene should be handled in a well-ventilated area, preferably in a fume hood. It should be stored in a tightly closed container away from heat, sparks, and sources of ignition. In case of a spill, it is recommended to use appropriate PPE such as gloves, goggles, and a lab coat. Refer to the Safety Data Sheet (SDS) for more detailed handling and disposal information.