Ethyl [(4-fluorophenyl)amino](oxo)acetate

Basic Information

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CAS Number

69065-91-4

Molecular Formula

C10H10FNO3

Molecular Weight

211.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

120-122°C

Density

1.293

Refractive Index

1.544

SMILES

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CCOC(=O)C(=O)NC1=CC=C(C=C1)F

InChI

InChI=1S/C10H10FNO3/c1-2-15-10(14)9(13)12-8-5-3-7(11)4-6-8/h3-6H,2H2,1H3,(H,12,13)

InChIKey

OUBZLXSQKQMFAH-UHFFFAOYSA-N

LogP

1.3273

Topological Polar Surface Area

55.400000000000006 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

237

Safety Information

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Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

A836346
ethyl2-((4-fluorophenyl)amino)-2-oxoacetate
ethyl [(4-fluorophenyl)carbamoyl]formate
Ethyl 2-[(4-Fluorophenyl)amino]-2-oxoacetate
AKOS000343866
SY063211
HMS2189O17
SCHEMBL11061083
OUBZLXSQKQMFAH-UHFFFAOYSA-N
EN300-235732
Ethyl 2-((4-fluorophenyl)amino)-2-oxoacetate
Ethyl (4-fluoroanilino)(oxo)acetate
Acetic acid,2-[(4-fluorophenyl)amino]-2-oxo-,ethyl ester
DTXSID40379000
CHEMBL1362951
Ethyl 4-fluorooxanilate
J-520562
MFCD00119045
ethyl 4'-fluorooxanilate
CS-0151548
ETHYL2-(4-FLUOROANILINO)-2-OXOACETATE
SMR000125300
MLS000539842
ethyl 2-(4-fluoroanilino)-2-oxoacetate
69065-91-4
FT-0680193
ethyl 2-(4-fluorophenylamino)-2-oxoacetate
2F-079
W18454
Acetic acid,2-[(4-fluorophenyl)amino]-2-oxo-, ethyl ester
Ethyl 2-(4-fluoroanilino)-2-oxoacetate

MDL Number

MFCD00119045

Customs Code

2924299090

FAQ

What are the physical and chemical properties of Ethyl [(4-fluorophenyl)amino](oxo)acetate (CAS: 69065-91-4)?

Ethyl [(4-fluorophenyl)amino](oxo)acetate is a white to off-white solid with a molecular weight of approximately 248.19 g/mol. It has a solubility of about 100 mg/L in water and is soluble in common organic solvents. This compound is moderately reactive, particularly towards nucleophiles and bases. It is stable under normal storage conditions but should be handled in a fume hood to avoid inhalation. It has limited reactivity with common laboratory reagents.

How is Ethyl [(4-fluorophenyl)amino](oxo)acetate (CAS: 69065-91-4) typically synthesized?

Ethyl [(4-fluorophenyl)amino](oxo)acetate is typically synthesized via a multi-step process involving the reaction of ethyl chloroacetate with 4-fluoroaniline followed by oxidation. This reaction is catalyzed by a suitable oxidizing agent such as sodium hypochlorite or potassium permanganate. The yield is generally around 70-80%, and the method provides high selectivity for the desired product.

What industries use Ethyl [(4-fluorophenyl)amino](oxo)acetate (CAS: 69065-91-4)?

Ethyl [(4-fluorophenyl)amino](oxo)acetate is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also of interest in polymer science where it can be used as a monomer. Additionally, it has applications in the production of sensors and other electronic components due to its chemical functionality.

What precautions should be taken when handling Ethyl [(4-fluorophenyl)amino](oxo)acetate (CAS: 69065-91-4)?

When handling Ethyl [(4-fluorophenyl)amino](oxo)acetate, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area, such as a fume hood, to prevent inhalation. In case of a spill, use absorbent materials and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed safety guidelines.