2-Ethoxybenzenesulfonyl chloride

Basic Information

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CAS Number

68800-33-9

Molecular Formula

C8H9ClO3S

Molecular Weight

220.68 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

60-64℃

SMILES

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CCOC1=CC=CC=C1S(=O)(=O)Cl

InChI

InChI=1S/C8H9ClO3S/c1-2-12-7-5-3-4-6-8(7)13(9,10)11/h3-6H,2H2,1H3

InChIKey

RWURYJNJYODVAL-UHFFFAOYSA-N

LogP

2.0128

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

245

Safety Information

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Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

AS-62475
F53457
2-Ethoxybenzene-1-sulfonyl chloride
DTXSID00596731
2-ethoxybenzenesulfonyl chloride
SCHEMBL8726763
RWURYJNJYODVAL-UHFFFAOYSA-N
2-Ethoxybenzene-1-sulfonylchloride
A866974
F2167-0062
AKOS010077101
EN300-125209
MFCD08706420
FT-0747662
68800-33-9
2-ETHOXY-BENZENESULFONYL CHLORIDE
2-Ethoxybenzenesulfonyl chloride
2-Ethoxy-benzenesulfonyl chloride
Benzenesulfonylchloride, 2-ethoxy-
2-Aethoxy-benzolsulfonylchlorid
Benzenesulfonylchloride,2-ethoxy
Phenetol-o-sulfonchlorid
2-ethoxybenzene-1-sulfonyl chloride

MDL Number

MFCD08706420

Customs Code

2909309090

FAQ

What are the physical and chemical properties of 2-Ethoxybenzenesulfonyl chloride (CAS: 68800-33-9)?

2-Ethoxybenzenesulfonyl chloride is a white crystalline solid with a molecular weight of approximately 243.24 g/mol. It is slightly soluble in water but soluble in organic solvents such as dichloromethane and ethanol. Chemically, it is a reactive compound, prone to hydrolysis under basic conditions. It can react with amines to form amides and with nucleophiles to form substituted products.

How is 2-Ethoxybenzenesulfonyl chloride (CAS: 68800-33-9) typically synthesized?

2-Ethoxybenzenesulfonyl chloride is typically synthesized by reacting p-ethoxybenzenesulfonic acid with thionyl chloride. The reaction is carried out under anhydrous conditions, and the yield is generally high with selectivity towards the desired product. The process requires careful control of temperature and the use of a suitable catalyst to achieve optimal results.

What industries use 2-Ethoxybenzenesulfonyl chloride (CAS: 68800-33-9)?

2-Ethoxybenzenesulfonyl chloride is used in various industries, particularly in pharmaceuticals for its role as an intermediate in the synthesis of medicinal compounds. It is also utilized in the production of polymers and as a reagent in organic synthesis for the preparation of other functionalized benzenesulfonates.

What precautions should be taken when handling 2-Ethoxybenzenesulfonyl chloride (CAS: 68800-33-9)?

When handling 2-Ethoxybenzenesulfonyl chloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up carefully using appropriate absorbent materials, and the substance should be stored in a cool, dry, and well-ventilated area away from incompatible materials. Always consult the Safety Data Sheet (SDS) for detailed information on handling and disposal.