2-(Chloromethyl)-4-nitrophenol

Basic Information

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CAS Number

68783-41-5

Molecular Formula

C7H6ClNO3

Molecular Weight

372.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

0.95 g/mL at 25 °C

Flash Point

>230 °F

Refractive Index

n20/D 1.477(lit.)

SMILES

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c1cc(c(cc1[N+](=O)[O-])CCl)O

InChI

InChI=1S/C7H6ClNO3/c8-4-5-3-6(9(11)12)1-2-7(5)10/h1-3,10H,4H2

InChIKey

PJNPZIYGODMAQE-UHFFFAOYSA-N

Complexity

437

Synonyms & References

English

DIMER ACID, HYDROGENATED
Tetrahydrocurcumin
1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
Sabiwhite
Tetrahydrodiferuloylmethane
1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
NSC687845
00U0645U03
Tetrahydrocucumin
3,5-Heptamedopme. 1,7-bis(hydroxy-3methoxyphenyl)heptane
THC (Tetra Hydro Curcumin)
BCP18621
BDBM50059985
s

MDL Number

MFCD00211870

FAQ

What are the physical and chemical properties of 2-(Chloromethyl)-4-nitrophenol (CAS: 68783-41-5)?

2-(Chloromethyl)-4-nitrophenol is a white crystalline solid with a molecular weight of approximately 225.03 g/mol. It has a solubility of about 0.025 g/100 mL in water. The compound is reactive, particularly towards nucleophiles, and is often used in synthesis due to its electrophilic aromatic properties. It readily undergoes nitration and substitution reactions.

How is 2-(Chloromethyl)-4-nitrophenol (CAS: 68783-41-5) typically synthesized?

2-(Chloromethyl)-4-nitrophenol is typically synthesized through the nitration of 2-(chloromethyl)phenol. The process involves reacting 2-(chloromethyl)phenol with a nitric acid/sulfuric acid mixture under controlled conditions to yield the nitro compound. The reaction can be carried out in a solvent such as acetic acid or another suitable medium.

What industries use 2-(Chloromethyl)-4-nitrophenol (CAS: 68783-41-5)?

2-(Chloromethyl)-4-nitrophenol is primarily used in the pharmaceutical industry for the synthesis of drugs and intermediates. It is also utilized in the production of dyes and pigments, as well as in the development of sensors and materials for electronic applications. Its versatility in various synthetic processes makes it a valuable compound in these sectors.

What precautions should be taken when handling 2-(Chloromethyl)-4-nitrophenol (CAS: 68783-41-5)?

When handling 2-(Chloromethyl)-4-nitrophenol, it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.