(1R,2R)-2-Aminocyclopentanol hydrochloride (1:1)

Basic Information

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CAS Number

68327-11-7

Molecular Formula

C5H12ClNO

Molecular Weight

137.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

No data available

Melting Point

180°C

Boiling Point

No data available

Density

1.7060

Flash Point

87.4℃

Vapor Pressure

No data available

SMILES

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C1CC(C(C1)O)N.Cl

InChI

InChI=1S/C5H11NO.ClH/c6-4-2-1-3-5(4)7;/h4-5,7H,1-3,6H2;1H/t4-,5-;/m1./s1

InChIKey

ZFSXKSSWYSZPGQ-TYSVMGFPSA-N

LogP

0.2802999999999998

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

65.1

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Sensitive to moisture

Synonyms & References

English

(1R,2R)-rel-2-Aminocyclopentanol hydrochloride
trans-2-Aminocyclopentanol HCl
(1R,2R)-2-Amino-cyclopentanol hydrochloride, 99%
rel-(1R,2R)-2-Aminocyclopentanol hydrochloride
Trans-(-)-2-aminocyclopentanol hydrochloride
SCHEMBL285952
AKOS015849508
MFCD02683551
Trans-(1R,2R)-2-Amino-Cyclopentanol Hydrochloride
(1R,2R)-trans-2-Aminocyclopentanol HCl
(1R,2R)-2-aminocyclopentanol hcl
(1R,2R)-trans-2-Aminocyclopentanol hydrochloride, 97%
trans-2-amino-cyclopentanol hydrochloride
AKOS015894235
AC-973
(1R,2R)-2-aminocyclopentanol hydrochloride;trans-(1R,2R)-2-Aminocyclopentanol Hydrochloride
Cyclopentanol, 2-amino-, hydrochloride, (1R,2R)-
J-500286
(1R,2R)-2-aminocyclopentan-1-ol hydrochloride
(1R,2R)-2-Aminocyclopentanol hydrochloride (1:1)
(1R,2R)-(-)-2-hydroxycyclopentylamine hydrochloride salt
(1R,2R)-trans-2-Aminocyclopentanol hydrochloride
(r,r)-2-amino-1-cyclopentanol hydrochloride
(1R,2R)-2-amino-1-cyclopentanol hydrochloride
(1R,2R)-2-aminocyclopentan-1-ol;hydrochloride
CS-W008557
(1R,2R)-2-azanylcyclopentan-1-ol hydrochloride
trans-2-Aminocyclopentanolhydrochloride
trans 2-aminocyclopentanol hydrochloride
ZFSXKSSWYSZPGQ-TYSVMGFPSA-N
EN300-60314

MDL Number

MFCD09834692

Customs Code

2922199090

FAQ

What are the physical and chemical properties of (1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7)?

(1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7) is a crystalline solid with a molecular weight of approximately 174.7 g/mol. It has a pKa of about 12.2. The compound is slightly soluble in water and ethanol but insoluble in hexane. It reacts readily with bases and can form salts with various metal ions. This compound is also known for its ability to form complexes with metal ions due to its basic nature.

How is (1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7) typically synthesized?

(1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7) is typically synthesized by first preparing 2-amino-1-cyclopentanol, which can be achieved through the reduction of 2-acyl-1-cyclopentanol with hydrogen in the presence of a catalyst like Raney nickel. Subsequently, this intermediate is treated with hydrochloric acid to generate the hydrochloride salt. The reaction is carried out in an acidic medium and involves high selectivity and good yield.

What industries use (1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7)?

The (1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor for the synthesis of various organic compounds and is also employed in the development of novel drugs. Additionally, it has applications in the production of certain polymers and as a chelating agent in analytical chemistry due to its ability to form stable complexes with metal ions.

What precautions should be taken when handling (1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7)?

When handling (1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats to protect against skin and eye irritation. Work should be performed in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbents, and the area should be thoroughly washed down. Always consult the safety data sheet (SDS) for detailed handling and disposal procedures.