How is (1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7) typically synthesized?

(1R,2R)-2-Aminocyclopentanol hydrochloride (CAS: 68327-11-7) is typically synthesized by first preparing 2-amino-1-cyclopentanol, which can be achieved through the reduction of 2-acyl-1-cyclopentanol with hydrogen in the presence of a catalyst like Raney nickel. Subsequently, this intermediate is treated with hydrochloric acid to generate the hydrochloride salt. The reaction is carried out in an acidic medium and involves high selectivity and good yield.