2-Fluoro-6-hydroxybenzoic acid

Basic Information

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CAS Number

67531-86-6

Molecular Formula

C7H5FO3

Molecular Weight

156.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

162.0 to 166.0 deg-C

Boiling Point

291.2℃ at 760 mmHg

Density

1.561

Flash Point

80.5℃

Refractive Index

1.441

SMILES

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C1=CC(=C(C(=C1)F)C(=O)O)O

InChI

InChI=1S/C7H5FO3/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,9H,(H,10,11)

InChIKey

BCEKGWWLVKXZKK-UHFFFAOYSA-N

LogP

1.2294999999999998

Topological Polar Surface Area

57.53 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

160

Safety Information

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GHS Hazard Pictograms

H302

H318

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-Fluorosalicylicacid
6-Fluorosalicylic acid
CL8047
SCHEMBL617480
2-Fluoro-6-hydroxybenzoic acid #
EN300-91482
AC-1797
SY016812
J-518761
FT-0621138
67531-86-6
Benzoic acid, 2-fluoro-6-hydroxy-
6-fluoro-2-hydroxobenzoic acid
6-Fluorosalicylic acid pound>>6-Fluoro-2-hydroxybenzoic acid
AKOS006222746
2-Fluoro-6-hydroxybenzoicacid;6-Fluoro-2-hydroxybenzoic acid
MFCD00052179
FS-1122
2-Fluoro-6-hydoxybenzoic acid
DTXSID50343035
6-Fluoro-2-hydroxybenzoic acid
AM61645
CS-W008162
A1773
Z1203162004
2-Fluoro-6-hydroxybenzoic acid
2-Fluoro-6-hydroxybenzoic acid, 97%
CHEMBL3092379
BCP30622
InChI=1/C7H5FO3/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,9H,(H,10,11
F0553

MDL Number

MFCD00052179

Customs Code

2918290000

FAQ

What are the physical and chemical properties of 2-Fluoro-6-hydroxybenzoic acid (CAS: 67531-86-6)?

2-Fluoro-6-hydroxybenzoic acid is a white or off-white crystalline solid with a molecular weight of approximately 172.05 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. Chemically, it is reactive towards bases and can undergo esterification and amide formation reactions.

How is 2-Fluoro-6-hydroxybenzoic acid (CAS: 67531-86-6) typically synthesized?

2-Fluoro-6-hydroxybenzoic acid can be synthesized through the reaction of 6-hydroxybenzoic acid with hydrogen fluoride in the presence of a suitable catalyst such as anhydrous zinc chloride. The process involves the introduction of a fluorine atom at the 2-position, followed by isolation and purification of the product.

What industries use 2-Fluoro-6-hydroxybenzoic acid (CAS: 67531-86-6)?

2-Fluoro-6-hydroxybenzoic acid finds application in pharmaceuticals, where it can be used as a precursor in drug synthesis. It is also utilized in the development of sensors and in the production of certain polymers. Additionally, it is explored for its potential in semiconductor applications.

What precautions should be taken when handling 2-Fluoro-6-hydroxybenzoic acid (CAS: 67531-86-6)?

When handling 2-Fluoro-6-hydroxybenzoic acid, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.