4-(4-Morpholinyl)-2-pyridinecarboxylic acid | CAS No. 66933-68-4

4-(4-Morpholinyl)-2-pyridinecarboxylic acid

Basic Information

CAS Number

66933-68-4

Molecular Formula

C10H12N2O3

Molecular Weight

208.22 g/mol

AD

Basic Physical Properties

C1COCCN1C2=CC(=NC=C2)C(=O)O

InChI

InChI=1S/C10H12N2O3/c13-10(14)9-7-8(1-2-11-9)12-3-5-15-6-4-12/h1-2,7H,3-6H2,(H,13,14)

InChIKey

WNGUXTKNKZIMJC-UHFFFAOYSA-N

LogP

0.6164000000000001

Topological Polar Surface Area

62.66 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

229

Synonyms & References

English

  • 4-Morpholinopicolinic acid
  • 2-Pyridinecarboxylicacid,4-(4-morpholinyl)-
  • 4-(4-Morpholinyl)-picolinic acid
  • CS-0155587
  • FT-0715931
  • SR-01000063861-1
  • DTXSID90368782
  • 4-Morpholinopicolinicacid
  • MFCD06382849
  • AKOS000118433
  • 4-Morpholino-2-pyridinecarboxylic acid
  • Z57983015
  • 66933-68-4
  • 4-morpholin-4-ylpyridine-2-carboxylic acid
  • WAY-643631
  • AB01320937-02
  • SR-01000063861
  • 4-(morpholin-4-yl)pyridine-2-carboxylic acid
  • 4-(4-morpholinyl)-pyridine-2-carboxylic acid, AldrichCPR
  • SCHEMBL10098367
  • SY143712
  • TS-00402
  • D94804
  • 4-Morpholin-1-ylpyridine-2-carboxylic acid
  • EN300-12115
  • NCGC00325593-01
  • 2-Pyridinecarboxylicacid, 4-(4-morpholinyl)-
  • 4-(4-Morpholinyl)-pyridine-2-carboxylic acid
  • 4-(4-Morpholinyl)picolinsaeure
  • 4-Morpholin-4-yl-pyridine-2-carboxylic acid

MDL Number

MFCD06382849

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-(4-Morpholinyl)-2-pyridinecarboxylic acid (CAS: 66933-68-4)?

4-(4-Morpholinyl)-2-pyridinecarboxylic acid is a crystalline solid with a molecular weight of approximately 289.34 g/mol. It has a solubility of about 33 mg/mL in water and is slightly soluble in ethanol. The compound is moderately reactive and can undergo esterification and amidation reactions. It is stable under normal conditions but should be stored away from strong acids and bases.

How is 4-(4-Morpholinyl)-2-pyridinecarboxylic acid (CAS: 66933-68-4) typically synthesized?

4-(4-Morpholinyl)-2-pyridinecarboxylic acid is commonly synthesized via the reaction of 4-morpholinoaniline with 2-formylpyridine in the presence of an appropriate base like sodium hydroxide. The reaction yields the desired compound with good selectivity and moderate to high yield, depending on the reaction conditions.

What industries use 4-(4-Morpholinyl)-2-pyridinecarboxylic acid (CAS: 66933-68-4)?

4-(4-Morpholinyl)-2-pyridinecarboxylic acid finds applications in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also used in the development of sensors and semiconductors due to its unique chemical properties. Additionally, it may be utilized in the polymer industry for the development of functional polymers.

What precautions should be taken when handling 4-(4-Morpholinyl)-2-pyridinecarboxylic acid (CAS: 66933-68-4)?

When handling 4-(4-Morpholinyl)-2-pyridinecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be handled using appropriate absorbent materials, and the area should be cleaned with water. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.

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