4-(4-Morpholinyl)-2-pyridinecarboxylic acid(CAS: 66933-68-4)

4-(4-Morpholinyl)-2-pyridinecarboxylic acid is a crystalline solid with a molecular weight of approximately 289.34 g/mol. It has a solubility of about 33 mg/mL in water and is slightly soluble in ethanol. The compound is moderately reactive and can undergo esterification and amidation reactions. It is stable under normal conditions but should be stored away from strong acids and bases.

4-(4-Morpholinyl)-2-pyridinecarboxylic acid is commonly synthesized via the reaction of 4-morpholinoaniline with 2-formylpyridine in the presence of an appropriate base like sodium hydroxide. The reaction yields the desired compound with good selectivity and moderate to high yield, depending on the reaction conditions.

4-(4-Morpholinyl)-2-pyridinecarboxylic acid finds applications in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also used in the development of sensors and semiconductors due to its unique chemical properties. Additionally, it may be utilized in the polymer industry for the development of functional polymers.

When handling 4-(4-Morpholinyl)-2-pyridinecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be handled using appropriate absorbent materials, and the area should be cleaned with water. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.