Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride | CAS No. 652158-84-4
Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride
Basic Information
CAS Number
652158-84-4
Molecular Formula
C6H10ClN3O3
Molecular Weight
207.62 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride
- DTXSID80719284
- CS-0260578
- Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate HCl
- ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate;hydrochloride
- EN300-7544039
- SCHEMBL25361925
- A867704
- Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate--hydrogen chloride (1/1)
- 652158-84-4
- Z2941518792
- AKOS016008907
- CBB15884
- Ethyl5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylatehydrochloride
MDL Number
MFCD18071516
FAQ
What are the physical and chemical properties of Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride (CAS: 652158-84-4)?
Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride is a crystalline solid with a molecular weight of approximately 289.7 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is known for its low reactivity in most conditions but can react with strong bases. It has a pKa of 1.2 and forms a stable salt in aqueous solutions.
How is Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride (CAS: 652158-84-4) typically synthesized?
Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride is typically synthesized through the reaction of ethyl 5-(chloromethyl)-1,3,4-oxadiazole-2-carboxylate with sodium amide in an aprotic solvent like dimethylformamide (DMF). The yield is around 85-90%, and the reaction is carried out under an inert atmosphere to prevent oxidation.
What industries use Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride (CAS: 652158-84-4)?
Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also utilized in the polymer industry for modifying polymer properties and in the sensor industry for developing chemical sensors due to its reactive functional groups.
What precautions should be taken when handling Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride (CAS: 652158-84-4)?
When handling Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and laboratory coats. The compound should be stored in a cool, dry place away from sources of heat and moisture. Spills should be handled with suitable absorbent materials and disposed of according to local hazardous waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on storage and handling.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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