Compound Q&A
How is Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride (CAS: 652158-84-4) typically synthesized?
Answer
Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride is typically synthesized through the reaction of ethyl 5-(chloromethyl)-1,3,4-oxadiazole-2-carboxylate with sodium amide in an aprotic solvent like dimethylformamide (DMF). The yield is around 85-90%, and the reaction is carried out under an inert atmosphere to prevent oxidation.
About
CAS No
652158-84-4
English Name
Ethyl 5-(aminomethyl)-1,3,4-oxadiazole-2-carboxylate hydrochloride
Molecular Formula
C6H10ClN3O3
Molecular Weight
207.62 g/mol
SMILES
CCOC(=O)C1=NN=C(O1)CN.Cl
InChIKey
VCDNOQLFRYWBBY-UHFFFAOYSA-N
Last Updated: 2026-03-26 08:46
