4,7-dichloroquinoline-3-carboxylic Acid

Basic Information

View in Editor

CAS Number

630067-21-9

Molecular Formula

C10H5Cl2NO2

Molecular Weight

242.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=CC2=C(C(=CN=C2C=C1Cl)C(=O)O)Cl

InChI

InChI=1S/C10H5Cl2NO2/c11-5-1-2-6-8(3-5)13-4-7(9(6)12)10(14)15/h1-4H,(H,14,15)

InChIKey

MLBIOMJMHCNLEL-UHFFFAOYSA-N

LogP

3.2398000000000007

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

262

Synonyms & References

English

4,7-Dichloroquinoline-3-carboxylic acid
4,7-dichloro-3-Quinolinecarboxylic acid
4,7-dichloro-quinoline-3-carboxylic acid
AC1MQ5W7
ACT10426
AK101836
ANW-62627
CTK8B9507
SureCN1178728
4,7-dichloroquinoline-3-carboxylic Acid
D86721
MLBIOMJMHCNLEL-UHFFFAOYSA-N
630067-21-9
DA-19497
SCHEMBL1178728
A904941
4,7-Dichloroquinoline-3-carboxylicacid
DTXSID50392548
AKOS002664604
SB69918

MDL Number

MFCD06255124

FAQ

What are the physical and chemical properties of 4,7-dichloroquinoline-3-carboxylic Acid (CAS: 630067-21-9)?

4,7-Dichloroquinoline-3-carboxylic Acid is a crystalline solid with a molecular weight of approximately 251.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like DMSO and acetonitrile. Chemically, it is reactive, particularly towards nucleophilic substitution and condensation reactions.

How is 4,7-dichloroquinoline-3-carboxylic Acid (CAS: 630067-21-9) typically synthesized?

4,7-Dichloroquinoline-3-carboxylic Acid is typically synthesized through the condensation of 4,7-dichloroquinoline with acetic anhydride in the presence of a catalyst like potassium carbonate. The reaction is performed in an inert atmosphere to prevent oxidation and achieve high selectivity and yield.

What industries use 4,7-dichloroquinoline-3-carboxylic Acid (CAS: 630067-21-9)?

4,7-Dichloroquinoline-3-carboxylic Acid is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly for the development of antiviral and anti-inflammatory drugs. It also finds applications in the polymer industry for the synthesis of polyquinolines and in the semiconductor industry for doping materials.

What precautions should be taken when handling 4,7-dichloroquinoline-3-carboxylic Acid (CAS: 630067-21-9)?

When handling 4,7-dichloroquinoline-3-carboxylic Acid, safety goggles and gloves should be worn to protect against skin contact and eye irritation. It should be stored in a well-ventilated area to minimize the risk of inhaling fumes. If a spill occurs, it should be cleaned up using appropriate PPE, and the Spill Response Data Sheet (SDS) should be referred to for detailed instructions.