4,7-dichloroquinoline-3-carboxylic Acid(CAS: 630067-21-9)

4,7-Dichloroquinoline-3-carboxylic Acid is a crystalline solid with a molecular weight of approximately 251.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like DMSO and acetonitrile. Chemically, it is reactive, particularly towards nucleophilic substitution and condensation reactions.

4,7-Dichloroquinoline-3-carboxylic Acid is typically synthesized through the condensation of 4,7-dichloroquinoline with acetic anhydride in the presence of a catalyst like potassium carbonate. The reaction is performed in an inert atmosphere to prevent oxidation and achieve high selectivity and yield.

4,7-Dichloroquinoline-3-carboxylic Acid is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly for the development of antiviral and anti-inflammatory drugs. It also finds applications in the polymer industry for the synthesis of polyquinolines and in the semiconductor industry for doping materials.

When handling 4,7-dichloroquinoline-3-carboxylic Acid, safety goggles and gloves should be worn to protect against skin contact and eye irritation. It should be stored in a well-ventilated area to minimize the risk of inhaling fumes. If a spill occurs, it should be cleaned up using appropriate PPE, and the Spill Response Data Sheet (SDS) should be referred to for detailed instructions.