(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate

Basic Information

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CAS Number

6283-74-5

Molecular Formula

C8H8O7

Molecular Weight

216.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

131.0 to 135.0 deg-C

Boiling Point

316.55°C (rough estimate)

Density

1.5197 (rough estimate)

Water Solubility

Soluble in methanol and dichloromethane. Slightly soluble in water.

Refractive Index

90 ° (C=0.5, CHCl3)

SMILES

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CC(=O)OC1C(C(=O)OC1=O)OC(=O)C

InChI

InChI=1S/C8H8O7/c1-3(9)13-5-6(14-4(2)10)8(12)15-7(5)11/h5-6H,1-2H3/t5-,6-/m1/s1

InChIKey

XAKITKDHDMPGPW-PHDIDXHHSA-N

LogP

-1.0668000000000002

Topological Polar Surface Area

95.97000000000003 Å²

Hydrogen Bond Donor/Acceptor

0 / 7

Complexity

300

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Moisture Sensitive

Synonyms & References

English

(3R,4R)-4-(acetyloxy)-2,5-dioxooxolan-3-yl acetate
EINECS 228-502-7
184636-89-3
D7XNF76O0K
6283-74-5
NSC-7712
O,O-Diacetyl tartaric acid anhydride
AS-68738
(R,R)-2,3-Diacetoxy-1,4-butanedioic Anhydride
D1911
Q27276225
(+)-O,O'-Diacetyl-L-tartaric anhydride, 97%
diacetyltartaric anhydride
[(3R,4R)-4-acetyloxy-2,5-dioxooxolan-3-yl] acetate
(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate
rel-(3R,4R)-2,5-dioxotetrahydrofuran-3,4-diyl diacetate
DIACETYLTARTARIC ANHYDRIDE, L-
(3R-trans)-Dihydro-2,5-dioxofuran-3,4-diyl diacetate
(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyldiacetate
Diacetyl-4-tartaric anhydride treated BSA
2,5-Furandione, 3,4-bis(acetyloxy)dihydro-, (3R,4R)-
AKOS000277852
D78416
(2R,3R)-Di-O-acetyltartaric Acid Anhydride
F0001-1696
UNII-D7XNF76O0K
(+)-Diacetyl-L-tartaric anhydride
MFCD00037918
(+)-O,O'-Diacetyl-L-tartaric anhydride
L-diacetyltartaric anhydride
(+)-O,O'-Diacetyl-L-tartaric anhydride, purum, >=97.0% (NT)

MDL Number

MFCD00037918

Customs Code

2918300090

FAQ

What are the physical and chemical properties of (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate (CAS: 6283-74-5)?

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate is a white or off-white crystalline solid. It has a molecular weight of approximately 148.18 g/mol and is slightly soluble in water. It is highly reactive and forms diesters, making it useful in various chemical reactions. The compound is insoluble in non-polar solvents but soluble in polar solvents such as ethanol and acetone.

How is (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate (CAS: 6283-74-5) typically synthesized?

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate can be synthesized via the acetylation of 2,5-dihydrofuran using acetic anhydride in the presence of a catalytic amount of sulfuric acid. The reaction is exothermic, and the product is obtained as a white or off-white solid after recrystallization. The method is known for its good yield and selectivity.

What industries use (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate (CAS: 6283-74-5)?

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate is used in the pharmaceutical industry for the synthesis of certain compounds and as a precursor in polymer synthesis. It is also utilized in the production of sensors and semiconductors due to its unique properties. Its versatility makes it a valuable chemical in various sectors of the chemical industry.

What precautions should be taken when handling (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate (CAS: 6283-74-5)?

When handling (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area, preferably under a fume hood, to minimize inhalation risks. In case of a spill, use personal protective equipment and clean up according to the safety data sheet (SDS). Always consult the SDS for detailed handling instructions and emergency procedures.