Compound Q&A

How is (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate (CAS: 6283-74-5) typically synthesized?

Answer

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate
(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate can be synthesized via the acetylation of 2,5-dihydrofuran using acetic anhydride in the presence of a catalytic amount of sulfuric acid. The reaction is exothermic, and the product is obtained as a white or off-white solid after recrystallization. The method is known for its good yield and selectivity.

About

CAS No 6283-74-5
English Name (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate
Molecular Formula C8H8O7
Molecular Weight 216.14 g/mol
SMILES CC(=O)OC1C(C(=O)OC1=O)OC(=O)C
InChIKey XAKITKDHDMPGPW-PHDIDXHHSA-N
Last Updated: 2025-11-01 22:12

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