(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate(CAS: 6283-74-5)

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate is a white or off-white crystalline solid. It has a molecular weight of approximately 148.18 g/mol and is slightly soluble in water. It is highly reactive and forms diesters, making it useful in various chemical reactions. The compound is insoluble in non-polar solvents but soluble in polar solvents such as ethanol and acetone.

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate can be synthesized via the acetylation of 2,5-dihydrofuran using acetic anhydride in the presence of a catalytic amount of sulfuric acid. The reaction is exothermic, and the product is obtained as a white or off-white solid after recrystallization. The method is known for its good yield and selectivity.

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate is used in the pharmaceutical industry for the synthesis of certain compounds and as a precursor in polymer synthesis. It is also utilized in the production of sensors and semiconductors due to its unique properties. Its versatility makes it a valuable chemical in various sectors of the chemical industry.

When handling (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area, preferably under a fume hood, to minimize inhalation risks. In case of a spill, use personal protective equipment and clean up according to the safety data sheet (SDS). Always consult the SDS for detailed handling instructions and emergency procedures.