(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine | CAS No. 61869-08-7
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
Basic Information
CAS Number
61869-08-7
Molecular Formula
C19H20FNO3
Molecular Weight
329.37 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
114-116°C
Boiling Point
451.674 °C at 760 mmHg
Density
1.1844 (estimate)
Flash Point
226.964 °C
Refractive Index
1.561
Synonyms & References
English
- NS00000037
- 41VRH5220H
- Paxetil
- (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
- PAROXETINE (MART.)
- (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
- (-)-(3S,4R)-4-(p-Fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine
- Paroxetina (INN-Spanish)
- DTXSID3023425
- Paroxetina
- Daparox
- (-)-Paroxetine
- paroxetine hydrochloride (anhydrous or hemihydrate)
- Arotin
- N06AB05
- KBio2_002232
- GTPL4790
- BPBio1_000949
- (3s,4r)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine
- Oxetine
- Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, (3S-trans)-
- Prestwick3_000851
- Besitram
- BRL-29060
- Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, trans-(+/-)-
- BRD-K37991163-003-02-7
- NCGC00025355-06
- PAROXETINE HCL HEMIHYDRATE
- BIDD:GT0673
- Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-,(3S,4R)-
- UNII-41VRH5220H
MDL Number
MFCD00869588
FAQ
What are the physical and chemical properties of (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine (CAS: 61869-08-7)?
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine is a white crystalline solid with a molecular weight of approximately 338.33 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. The compound exhibits moderate reactivity with nucleophiles and electrophiles. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.
How is (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine (CAS: 61869-08-7) typically synthesized?
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine is synthesized through the reaction of 4-fluorophenylpiperidine with 1,3-benzodioxol-5-yloxy methyl bromide in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. The product is purified by recrystallization from ethanol to obtain the crystalline form.
What industries use (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine (CAS: 61869-08-7)?
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine is primarily used in the pharmaceutical industry for the development of novel drugs. It is also of interest in polymer research for its potential use in the synthesis of advanced materials. Additionally, it can be used in the production of sensors and semiconductors due to its unique chemical properties.
What precautions should be taken when handling (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine (CAS: 61869-08-7)?
When handling (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine, it is crucial to work in a well-ventilated area and use a fume hood. Wear appropriate personal protective equipment (PPE) such as safety goggles, gloves, and a lab coat. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions to ensure safe laboratory practices.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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