(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine(CAS: 61869-08-7)

(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine is a white crystalline solid with a molecular weight of approximately 338.33 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. The compound exhibits moderate reactivity with nucleophiles and electrophiles. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.

(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine is synthesized through the reaction of 4-fluorophenylpiperidine with 1,3-benzodioxol-5-yloxy methyl bromide in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. The product is purified by recrystallization from ethanol to obtain the crystalline form.

(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine is primarily used in the pharmaceutical industry for the development of novel drugs. It is also of interest in polymer research for its potential use in the synthesis of advanced materials. Additionally, it can be used in the production of sensors and semiconductors due to its unique chemical properties.

When handling (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine, it is crucial to work in a well-ventilated area and use a fume hood. Wear appropriate personal protective equipment (PPE) such as safety goggles, gloves, and a lab coat. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions to ensure safe laboratory practices.