Compound Q&A
How is (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine (CAS: 61869-08-7) typically synthesized?
Answer
![(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine](https://static.chemtradehub.com/structs/618/61869-08-7-59f8.webp "(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine")
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine is synthesized through the reaction of 4-fluorophenylpiperidine with 1,3-benzodioxol-5-yloxy methyl bromide in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. The product is purified by recrystallization from ethanol to obtain the crystalline form.
About
CAS No
61869-08-7
English Name
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
Molecular Formula
C19H20FNO3
Molecular Weight
329.37 g/mol
SMILES
C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
InChIKey
AHOUBRCZNHFOSL-YOEHRIQHSA-N
Last Updated: 2025-09-09 08:06
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