1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde | CAS No. 618101-78-3

1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde

Basic Information

CAS Number

618101-78-3

Molecular Formula

C16H10FN3O3

Molecular Weight

311.27 g/mol

AD

Basic Physical Properties

C1=CC=C(C(=C1)N2C=C(C(=N2)C3=CC=C(C=C3)[N+](=O)[O-])C=O)F

InChI

InChI=1S/C16H10FN3O3/c17-14-3-1-2-4-15(14)19-9-12(10-21)16(18-19)11-5-7-13(8-6-11)20(22)23/h1-10H

InChIKey

PKQFKQFKYSPRBU-UHFFFAOYSA-N

LogP

3.92230

Complexity

437

Synonyms & References

English

  • 1-(2-FLUOROPHENYL)-3-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE
  • MFCD05150460
  • CS-D0346
  • DB-258697
  • 618101-78-3
  • s11362
  • 1-(2-fluorophenyl)-3-(4-nitrophenyl)pyrazole-4-carbaldehyde
  • AKOS024412192

MDL Number

MFCD05150460

FAQ

What are the physical and chemical properties of 1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS: 618101-78-3)?

1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde is a crystalline compound with a molecular weight of approximately 340.08 g/mol. It has low solubility in water but is more soluble in organic solvents such as ethanol and acetonitrile. The compound exhibits typical reactivity for aldehydes, including nucleophilic addition reactions and condensation reactions.

How is 1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS: 618101-78-3) typically synthesized?

1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde can be synthesized by the reaction of 2-fluorophenyl hydrazine with 4-nitrobenzaldehyde. The synthesis typically involves condensation reactions under acidic conditions, with yields ranging from 70-85%. Suitable catalysts include acetic acid and other Lewis acids.

What industries use 1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS: 618101-78-3)?

1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde finds applications in the pharmaceutical industry for the synthesis of various drug intermediates. It is also used in the sensor technology and semiconductor industries due to its unique chemical properties and potential for electronic applications.

What precautions should be taken when handling 1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS: 618101-78-3)?

When handling 1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde, proper personal protective equipment (PPE) should be worn, including gloves, safety glasses, and a lab coat. Fume hoods should be used during handling to minimize inhalation risks. Spills should be handled carefully using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill and emergency procedures. Storage should be in a cool, dry place away from direct sunlight and other reactive materials.

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