Compound Q&A
How is 1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS: 618101-78-3) typically synthesized?
Answer
1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde can be synthesized by the reaction of 2-fluorophenyl hydrazine with 4-nitrobenzaldehyde. The synthesis typically involves condensation reactions under acidic conditions, with yields ranging from 70-85%. Suitable catalysts include acetic acid and other Lewis acids.
About
CAS No
618101-78-3
English Name
1-(2-Fluorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde
Molecular Formula
C16H10FN3O3
Molecular Weight
311.27 g/mol
SMILES
C1=CC=C(C(=C1)N2C=C(C(=N2)C3=CC=C(C=C3)[N+](=O)[O-])C=O)F
InChIKey
PKQFKQFKYSPRBU-UHFFFAOYSA-N
Last Updated: 2026-04-02 10:24
