(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid | CAS No. 603130-13-8

(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid

Basic Information

CAS Number

603130-13-8

Molecular Formula

C11H19NO5

Molecular Weight

245.27 g/mol

AD

Basic Physical Properties

Physical State

White to Yellow Solid

CC(C)(C)OC(=O)NC1CCC(OC1)C(=O)O

InChI

InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-7-4-5-8(9(13)14)16-6-7/h7-8H,4-6H2,1-3H3,(H,12,15)(H,13,14)/t7-,8+/m1/s1

InChIKey

NROSRTMHTJHLLE-SFYZADRCSA-N

LogP

1.1432999999999998

Topological Polar Surface Area

84.86 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

297

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • (2S,5R)-5-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic Acid
  • (2S,5R)-5-((tert-Butoxycarbonyl)amino)tetrahydro-2H-pyran-2-carboxylic acid
  • (2S,5R)-5-[(2-methylpropan-2-yl)oxycarbonylamino]oxane-2-carboxylic acid
  • (2S,5R)-5-Boc-amino-tetrahydropyran-2-carboxylic acid
  • (2S,5R)-5-{[(tert-butoxy)carbonyl]amino}oxane-2-carboxylic acid
  • trans-5-(Boc-amino)-tetrahydro-pyran-2-carboxylic acid
  • 2,6-anhydro-5-[(tert-butoxycarbonyl)amino]-3,4,5-trideoxy-L-erythro-hexonic acid
  • AK165103
  • (2S,5R)-5-tert-butoxycarbonylamino-tetrahydro-pyran-2-carb
  • (2S,5R)-5-(tert-butoxycarbonylamino)tetrahydropyran-2-carboxylic acid
  • (2S, 5R)-5-tert-Butoxycarbonylamino-tetrahydro-pyran-2-carboxylic acid
  • (2S,5R)-5-[(2-methylpropan-2-yl)oxycarbonylamino]oxane-2-carboxylic Acid
  • SCHEMBL4523657
  • CS-0039053
  • AKOS025147237
  • DB-309818
  • (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid
  • MFCD20261452
  • DTXSID70448490
  • (2S,5R)-5-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic Acid; L-erythro-Hexonic acid, 2,6-anhydro-3,4,5-trideoxy-5-[[(1,1-dimethylethoxy)carbonyl]amino]-; 2,6-Anhydro-3,4,5-trideoxy-5-[[(1,1-dimethylethoxy)carbonyl]amino]-L-erythro-hexonic acid; (2S,5R)-5-(tert-Butoxycarbonylamino)tetrahydropyran-2-carboxylic acid;
  • (2S,5R)-5-BOC-AMINO-TETRAHYDROPYRAN-2-CARBOXYLIC ACID
  • (2S,5R)-5-{[(tert-butoxy)carbonyl]amino}oxane-2-
  • (2S,5R)-5-(tert-butoxycarbonyl)-tetrahydro-2H-pyran-2-carboxylic acid;(2S,5R)-5-((tert-Butoxycarbonyl)amino)tetrahydro-2H-pyran-2-carboxylic acid
  • AS-30023
  • PB36003
  • A852652
  • (2S,5R)-5-tert-butoxycarbonylamino-tetrahydro-pyran-2-carboxylic acid
  • AMY12307
  • (2S,5R)-5-((tert-Butoxycarbonyl)amino)tetrahydro-2H-pyran-2-carboxylicacid
  • 603130-13-8
  • (2S,5R)-5-(tert-Butoxycarbonylamino)tetrahydro-2h-pyran-2-carboxylic acid

MDL Number

MFCD20261452

FAQ

What are the physical and chemical properties of (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8)?

(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) has a crystalline form, with a molecular weight of approximately 280.44 g/mol. It is sparingly soluble in water but more soluble in organic solvents like methanol and ethanol. The compound shows moderate reactivity, particularly towards nucleophilic substitution reactions. It is stable under normal conditions but should be stored away from strong acids and bases to prevent degradation.

How is (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) typically synthesized?

(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) can be synthesized through a multi-step process, starting with (2S,5R)-tetrahydro-2H-pyran-2-carboxylic acid. This is followed by the introduction of a tert-butoxycarbonyl group via a standard Boc protection method, utilizing tert-butyldimethylsilyl triflate as a coupling agent. The reaction typically yields a high purity product with good selectivity.

What industries use (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8)?

(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) is commonly used in the pharmaceutical industry for drug synthesis and in polymer chemistry for the development of functional polymers. It also finds applications in the production of sensors and semiconductors, where its unique chemical properties are utilized to enhance performance and functionality.

What precautions should be taken when handling (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8)?

When handling (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with care, using appropriate absorbents and disposing of the material according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...