Compound Q&A
How is (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) typically synthesized?
Answer
![(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid](https://static.chemtradehub.com/structs/603/603130-13-8-fd6b.webp "(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid")
(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) can be synthesized through a multi-step process, starting with (2S,5R)-tetrahydro-2H-pyran-2-carboxylic acid. This is followed by the introduction of a tert-butoxycarbonyl group via a standard Boc protection method, utilizing tert-butyldimethylsilyl triflate as a coupling agent. The reaction typically yields a high purity product with good selectivity.
About
CAS No
603130-13-8
English Name
(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid
Molecular Formula
C11H19NO5
Molecular Weight
245.27 g/mol
SMILES
CC(C)(C)OC(=O)NC1CCC(OC1)C(=O)O
InChIKey
NROSRTMHTJHLLE-SFYZADRCSA-N
Last Updated: 2025-10-28 10:54
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