(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid(CAS: 603130-13-8)

(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) has a crystalline form, with a molecular weight of approximately 280.44 g/mol. It is sparingly soluble in water but more soluble in organic solvents like methanol and ethanol. The compound shows moderate reactivity, particularly towards nucleophilic substitution reactions. It is stable under normal conditions but should be stored away from strong acids and bases to prevent degradation.

(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) can be synthesized through a multi-step process, starting with (2S,5R)-tetrahydro-2H-pyran-2-carboxylic acid. This is followed by the introduction of a tert-butoxycarbonyl group via a standard Boc protection method, utilizing tert-butyldimethylsilyl triflate as a coupling agent. The reaction typically yields a high purity product with good selectivity.

(2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8) is commonly used in the pharmaceutical industry for drug synthesis and in polymer chemistry for the development of functional polymers. It also finds applications in the production of sensors and semiconductors, where its unique chemical properties are utilized to enhance performance and functionality.

When handling (2S,5R)-5-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-2-carboxylic acid (CAS: 603130-13-8), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with care, using appropriate absorbents and disposing of the material according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.