2,5-Dichlorobenzamide

Basic Information

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CAS Number

5980-26-7

Molecular Formula

C7H5Cl2NO

Molecular Weight

190.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

170-172°C

Boiling Point

262.8°C at 760 mmHg

SMILES

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C1=CC(=C(C=C1Cl)C(=O)N)Cl

InChI

InChI=1S/C7H5Cl2NO/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H2,10,11)

InChIKey

NMHJIYQWKWHDSX-UHFFFAOYSA-N

LogP

2.0923

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

163

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Benzamide, 2,5-dichloro-
MFCD00017609
DTXSID7073985
IXAZOMIB METABOLITE M4 OR M20
NMHJIYQWKWHDSX-UHFFFAOYSA-N
Benzamide,2,5-dichloro-
D82410
ML750445
F4ZCW2E9FU
SY041304
CS-W015918
FT-0610300
DS-18490
AKOS008937418
5980-26-7
NS00034241
AMY14505
SCHEMBL1086528
2,5-DICHLOROBENZAMIDE
UNII-F4ZCW2E9FU
2,5-Dichlorobenzamide
2,3-Dichlorobenzamide
2,5-Dichloro-benzamide
KSC610K1T
EBD79354
VZ22201
AS02859
ZB008803
ST2403704
ST50407490

MDL Number

MFCD00017609

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 2,5-Dichlorobenzamide (CAS: 5980-26-7)?

2,5-Dichlorobenzamide (CAS: 5980-26-7) is a solid with a crystalline form. Its molecular weight is approximately 190.03 g/mol. It has a low solubility in water but is more soluble in organic solvents. It is relatively stable but can react with strong bases. It is commonly used in the synthesis of other compounds due to its reactivity with amides.

How is 2,5-Dichlorobenzamide (CAS: 5980-26-7) typically synthesized?

2,5-Dichlorobenzamide (CAS: 5980-26-7) is typically synthesized by the amidation of 2,5-dichlorobenzoic acid with a primary amine. Commonly, the reaction is carried out in the presence of a coupling reagent like dicyclohexylcarbodiimide (DCC) and a base like 4-(dimethylamino)pyridine (DMAP). The process yields a highly selective product with good yield.

What industries use 2,5-Dichlorobenzamide (CAS: 5980-26-7)?

2,5-Dichlorobenzamide (CAS: 5980-26-7) is used in various industries. It plays a significant role in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also used in the polymer industry for the modification of polymers and in the sensor industry for the development of chemical sensors. Additionally, it has applications in the semiconductor industry for doping purposes.

What precautions should be taken when handling 2,5-Dichlorobenzamide (CAS: 5980-26-7)?

When handling 2,5-Dichlorobenzamide (CAS: 5980-26-7), it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.