Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (1:1) | CAS No. 57591-61-4
Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (1:1)
Basic Information
CAS Number
57591-61-4
Molecular Formula
C9H12ClNO3
Molecular Weight
217.65 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
187-190 °C
Boiling Point
335℃ at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- A854379
- AM20060676
- 57591-61-4
- GS-4249
- DTXSID10528780
- D-4-hydroxyphenylglycine methyl ester HCl
- AC-33864
- SCHEMBL1584177
- Methyl (2R)-amino(4-hydroxyphenyl)acetate--hydrogen chloride (1/1)
- (R)-METHYL 2-AMINO-2-(4-HYDROXYPHENYL)ACETATE HCL
- (R)-Amino-(4-hydroxyphenyl)acetic acid methyl ester hydrochloride
- methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate hydrochloride
- UYCKVJUNDXPDJH-DDWIOCJRSA-N
- (R)-Amino-(4-hydroxyphenyl)acetic acid methyl ester HCl
- (R)-Methyl2-amino-2-(4-hydroxyphenyl)acetatehydrochloride
- D-4-Hydroxyphenylglycine methyl ester hydrochloride
- AKOS015893992
- methyl(R)-amino-(4-hydroxyphenyl)acetate hydrochloride
- (R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate hydrochloride
- (R)-Amino-(4-hydroxyphenyl)acetic acid methyl ester hydrochloride, 97%
- CS-W014809
- methyl (R)-amino-(4-hydroxyphenyl)acetate hydrochloride
- D-p-Hydroxyphenylglycine methyl ester hydrochloride
- MFCD01862152
- methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate;hydrochloride
- R-Amino-(4-Hydroxyphenyl)Acetic Acid Methyl Ester Hydrochloride
- (R)-Amino-(4-Hydroxyphenyl)Acetic Acid Methyl Ester Hydrochloride
- D(-)Para-Hydroxyphenylglycine Methyl Ester
- D-4-Hydroxyphenylglycine methyl ester HCl
- methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate,hydrochloride
- (R)-(4-hydroxyphenyl)glycine methylester hydrochloride
MDL Number
MFCD01862152
Customs Code
2922509090
FAQ
What are the physical and chemical properties of Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4)?
Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4) is a crystalline white powder with a molecular weight of approximately 274.8 g/mol. It has a solubility of about 50 mg/mL in water and is slightly soluble in ethanol. This compound is reactive towards bases and can undergo hydrolysis under acidic conditions. It is stable under normal storage conditions but should be protected from strong acids and moisture.
How is Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4) typically synthesized?
Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4) is typically synthesized by reacting 4-hydroxyacetophenone with methylamine in the presence of a catalytic amount of a chiral resolving agent, such as (S)-(-)-1-phenylethanol. The reaction mixture is then treated with hydrochloric acid to form the hydrochloride salt. The process achieves high selectivity and yields around 90% of the desired enantiomer.
What industries use Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4)?
Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4) is primarily used in the pharmaceutical industry for the synthesis of chiral intermediates in drug development. It is also utilized in the production of certain pesticides and as a chiral ligand in asymmetric catalysis for the synthesis of enantiopure compounds.
What precautions should be taken when handling Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4)?
When handling Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from strong acids and moisture. In case of a spill, handle it in a fume hood and follow the standard laboratory safety procedures. Always consult the Material Safety Data Sheet (MSDS) for detailed instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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