Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (1:1)(CAS: 57591-61-4)

Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4) is a crystalline white powder with a molecular weight of approximately 274.8 g/mol. It has a solubility of about 50 mg/mL in water and is slightly soluble in ethanol. This compound is reactive towards bases and can undergo hydrolysis under acidic conditions. It is stable under normal storage conditions but should be protected from strong acids and moisture.

Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4) is typically synthesized by reacting 4-hydroxyacetophenone with methylamine in the presence of a catalytic amount of a chiral resolving agent, such as (S)-(-)-1-phenylethanol. The reaction mixture is then treated with hydrochloric acid to form the hydrochloride salt. The process achieves high selectivity and yields around 90% of the desired enantiomer.

Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4) is primarily used in the pharmaceutical industry for the synthesis of chiral intermediates in drug development. It is also utilized in the production of certain pesticides and as a chiral ligand in asymmetric catalysis for the synthesis of enantiopure compounds.

When handling Methyl (2R)-amino(4-hydroxyphenyl)acetate hydrochloride (CAS: 57591-61-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from strong acids and moisture. In case of a spill, handle it in a fume hood and follow the standard laboratory safety procedures. Always consult the Material Safety Data Sheet (MSDS) for detailed instructions.