3,4-Dichloropyridine

Basic Information

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CAS Number

55934-00-4

Molecular Formula

C5H3Cl2N

Molecular Weight

147.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Colorless

Melting Point

22-23 C

Boiling Point

182-183℃

Density

1.388±0.06 g/cm3(Predicted)

Flash Point

78.2℃

Refractive Index

1.553

SMILES

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C1=CN=CC(=C1Cl)Cl

InChI

InChI=1S/C5H3Cl2N/c6-4-1-2-8-3-5(4)7/h1-3H

InChIKey

ZMPYQKNNUHPTLT-UHFFFAOYSA-N

LogP

2.3884000000000007

pKa

1.81±0.10(Predicted)

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

76.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

CS-W004811
J-511146
3,4,dichloropyridine
SCHEMBL952595
DTXSID30371114
AM20070032
FT-0640348
F0001-1466
PS-6123
SY010516
MFCD01861989
3,4-Dichloropyridine
A8067
Pyridine, 3,4-dichloro-
55934-00-4
AKOS005257645
EN300-97312
Z1575308475
3,4-DICHLOROPYRIDINE
3,4-Dichloropyridine ,97%
3,4- twochlorine pyridine
3,4-Dichloropyridine ISO 9001：2015 REACH
Pyridine, 3,4-dichloro

MDL Number

MFCD01861989

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3,4-Dichloropyridine (CAS: 55934-00-4)?

3,4-Dichloropyridine is a solid at room temperature with a crystalline form. Its molecular weight is 180.01 g/mol. It has limited water solubility but is soluble in common organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but can react with strong bases to form pyridine. It is an important intermediate in the synthesis of various pharmaceuticals and materials.

How is 3,4-Dichloropyridine (CAS: 55934-00-4) typically synthesized?

3,4-Dichloropyridine is commonly synthesized via the reaction of 2-chloropyridine with chlorine gas. This process involves the substitution of a hydrogen atom with a chlorine atom at the 3 and 4 positions. Other methods include the chlorination of pyridine using thionyl chloride as a catalyst, which provides high selectivity and yield.

What industries use 3,4-Dichloropyridine (CAS: 55934-00-4)?

3,4-Dichloropyridine is widely used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the polymer industry as a precursor for the production of various polymers and in the electronics sector for the manufacturing of semiconductors. Additionally, it is utilized in the development of sensors and as a reagent in analytical chemistry.

What precautions should be taken when handling 3,4-Dichloropyridine (CAS: 55934-00-4)?

When handling 3,4-Dichloropyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be handled carefully using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information and emergency procedures.