3,4-Dichloropyridine(CAS: 55934-00-4)

3,4-Dichloropyridine is a solid at room temperature with a crystalline form. Its molecular weight is 180.01 g/mol. It has limited water solubility but is soluble in common organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but can react with strong bases to form pyridine. It is an important intermediate in the synthesis of various pharmaceuticals and materials.

3,4-Dichloropyridine is commonly synthesized via the reaction of 2-chloropyridine with chlorine gas. This process involves the substitution of a hydrogen atom with a chlorine atom at the 3 and 4 positions. Other methods include the chlorination of pyridine using thionyl chloride as a catalyst, which provides high selectivity and yield.

3,4-Dichloropyridine is widely used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the polymer industry as a precursor for the production of various polymers and in the electronics sector for the manufacturing of semiconductors. Additionally, it is utilized in the development of sensors and as a reagent in analytical chemistry.

When handling 3,4-Dichloropyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be handled carefully using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information and emergency procedures.